3 citations
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October 2024 in “Cancers” Skin side effects from melanoma immunotherapy are common and may indicate better survival.
12 citations
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June 2010 in “Journal of dermatology” Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.
25 citations
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May 2018 in “Clinical & Translational Oncology” New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
7 citations
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May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
1 citations
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January 2005 in “Experimental Dermatology” MC-1R in skin cells may influence inflammation and collagen production.
15 citations
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June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
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September 2022 in “Frontiers in pharmacology” Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
2 citations
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August 2025 in “Reports — Medical Cases Images and Videos” A rare pigmented skin tumor called melanotrichoblastoma was diagnosed in a 51-year-old woman.
January 2024 in “Clinical, cosmetic and investigational dermatology” Dermatologists should customize cosmetic treatments for dark-skinned patients to minimize risks and complications.
3 citations
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October 2020 in “Journal of Investigative Dermatology” Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
33 citations
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December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
349 citations
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January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
8 citations
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August 2015 in “Journal of dermatological science” Rhododendrol in skin-whitening products can cause skin depigmentation and immune reactions.
1 citations
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April 2004 in “Cancer” Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.
9 citations
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June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
January 1972 in “NBER Chapters” Melatonin may protect skin from radiation, but its effects on aging and hair growth are unclear.
10 citations
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May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
39 citations
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March 2017 in “Dermatologic clinics” UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
10 citations
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October 2023 in “Indian Dermatology Online Journal” Choose melasma treatments based on individual needs and local availability.
8 citations
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January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
1 citations
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January 2018 in “Methods in molecular biology” The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
2 citations
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January 2002 Melanin and melanocytes contribute to the brown pigmentation in stasis dermatitis.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Safflower extract increases melanin production in certain skin cells without harming them.
September 2022 in “Frontiers in Medicine” New treatments and drugs show promise for improving skin pigmentation and regeneration.
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January 2018 in “European journal of dermatology/EJD. European journal of dermatology” The girl's regrown brown hair had less of certain pigments than her original black hair.
June 2023 in “NILES Journal forGeriatric and Gerontology/NILES Journal for Geriatric and Gerontology” Oral tranexamic acid is a safe and effective treatment for melasma.
35 citations
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January 1981 January 2006 in “Chinese Journal of Dermatology” Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
40 citations
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.