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Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

Repurposing existing drugs can improve cancer treatment but faces challenges.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Alkylating agents can kill cancer cells but may cause skin and allergic reactions.

Combining specific nanoparticles with immune therapy significantly improves cancer treatment.

Finasteride's metabolites were identified, helping understand how the drug is processed in the body.

Metformin improved menstrual cycles and cholesterol but didn't change weight or hormone levels in the short term for overweight PCOS women.

Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

An 11-year-old girl's hair regrew after treating her thyroid condition with carbimazole.

Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.

Methotrexate effectively controls eye inflammation in Japanese patients with non-infectious uveitis but requires careful monitoring for side effects.

A new method creates unique chemical structures that could improve drug discovery.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

Cimetidine cream shows potential for treating warts and female-pattern hair loss.

Cimetidine does not significantly reduce hair growth in hirsutism.

Multitarget drugs are needed to better treat complex diseases.

Mycophenolate mofetil is safer and more effective than cyclophosphamide for treating lupus nephritis.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

Targeting METTL1 may help slow papillary thyroid cancer growth and spread.

INTASYL is a promising, adaptable RNAi technology for treating skin cancers.

New anti-acne medications are being tested to offer alternatives to current treatments.

High-dose methotrexate can cause severe skin and nail issues.