2 citations
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January 2021 in “American Journal of Case Reports” A 13-year-old boy with a rare genetic condition survived a heart attack and improved with treatment.
October 2021 in “Journal of Investigative Dermatology” Skin changes in Pseudoxanthoma elasticum patients can indicate the severity of related health issues.
March 2013 in “The Journal of Urology” Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.
January 2021 in “ABC Heart Failure & Cardiomyopathy” When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.
April 2024 in “Research Square (Research Square)” A 27-year-old with APS-1 showed improvement in symptoms after treatment.
January 2024 in “Wiadomości Lekarskie” Aortic aneurysm treatment has shifted to less invasive methods, improving safety and outcomes.
April 2026 in “Quality in Sport” Anabolic-androgenic steroids increase the risk of heart problems.
17 citations
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June 2019 in “Cellular signalling” Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
January 2024 in “Wiadomości Lekarskie” AI and new therapies show promise in medicine, especially for cancer and regenerative treatments.
336 citations
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August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
Sphingosine 1-phosphate affects inflammation and gene expression in different aorta cells.
S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
1 citations
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June 2024 in “Frontiers in Physiology” Endoplasmic reticulum stress plays a key role in developing atherosclerosis.
8 citations
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March 2018 in “Expert Review of Respiratory Medicine” Inhalation therapy may repair and protect elastin in the lungs of COPD patients.
237 citations
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February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
3 citations
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January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.
1415 citations
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October 2007 in “European Journal of Epidemiology” The Rotterdam Study investigates diseases in older adults and has produced many research findings.
991 citations
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January 2011 in “Nature Reviews Endocrinology” The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
883 citations
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August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
815 citations
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April 2010 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS should be screened for heart disease risk and manage their health to prevent it.
418 citations
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June 2003 in “Endocrine Reviews” While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.
414 citations
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August 2005 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.
373 citations
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September 2009 in “Obstetrics & Gynecology” The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.
359 citations
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September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
266 citations
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November 2013 in “European Journal of Epidemiology” The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
219 citations
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September 2009 in “European journal of epidemiology” The Rotterdam Study aims to understand various diseases in older adults.
215 citations
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January 2011 in “Reproductive Biology and Endocrinology” About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
155 citations
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March 2006 in “The American Journal of Medicine” Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
60 citations
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May 2011 in “Endocrinology and Metabolism Clinics of North America” Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
51 citations
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November 2011 in “Reproductive Biology and Endocrinology” About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.