Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.
January 2005 in “中华医学杂志:英文版” Scar tissue may regenerate sweat glands from remaining glands or stem cells.
72 citations
,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
18 citations
,
January 1992 in “Dermatology” A 4-year-old girl has a rare condition causing hairlessness and skin bumps, but normal teeth and sweating.
April 2018 in “Journal of Investigative Dermatology” STIM1 is essential for sweat secretion.
April 2020 in “Journal of the Endocrine Society” Taking thyroid medication reduced the patient's pituitary gland swelling and improved her symptoms.
89 citations
,
August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
9 citations
,
December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
1 citations
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September 2020 in “Journal of Dermatological Science” The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.
January 2025 in “Haematology International Journal” These ovarian conditions cause high testosterone levels.
19 citations
,
January 2014 in “International Journal of Medical Sciences” Abnormal activation of hair follicle stem cells and Wnt/β-catenin signaling contributes to sebaceous neoplasms.
October 1991 in “Archives of Dermatology” The woman has a skin condition involving nodules, scars, and hair loss.
41 citations
,
April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.
48 citations
,
April 1995 in “PubMed” Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.
4 citations
,
January 2019 in “Journal of cutaneous pathology” The mTOR pathway may be involved in the development of hair follicle tumors, with higher activity in malignant tumors.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa tunnels have different microenvironments, suggesting targeted treatments could be more effective.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa tunnels have different microenvironments, suggesting targeted treatments could be more effective.
January 2014 in “Pathology” RET mutation is important in familial medullary thyroid carcinoma, and BRAF mutation in papillary thyroid carcinoma is linked to more aggressive cancer and higher death rates.
April 2018 in “Journal of Investigative Dermatology” The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
2 citations
,
January 2002 in “Zhiwu Yanjiu” Capitate trichomes have more endoplasmic reticulum and vacuoles, while peltate trichomes have more plastids and larger subcuticular spaces.
8 citations
,
May 1996 in “Endocrinology” Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
December 2022 in “Journal of Paediatrics and Child Health” A 14-year-old girl experienced severely itchy lesions in the armpits and pubic region for 6 months, following laser treatment and axillary hair loss. The lesions were skin-coloured to yellowish-brown papules, 1–2 mm in size, with a dome-shaped, smooth surface, distributed around hair follicles. Despite treatment with ketoconazole cream for a suspected fungal infection, there was no improvement. The document did not provide the diagnosis, which was referenced on another page.
4 citations
,
March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
9 citations
,
June 2014 in “British Journal of Dermatology” The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
1 citations
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February 2022 in “Experimental Dermatology” Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.
1 citations
,
July 2009 in “Journal of dermatology” A 29-year-old man had a jaw plaque diagnosed as follicular mucinosis, linked to nestin-positive hair follicle stem cells.
9 citations
,
November 2013 in “Gynecological Endocrinology” A woman had high testosterone due to an ovarian issue, which was fixed with surgery.
4 citations
,
July 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.
2 citations
,
March 2019 in “Journal of Histochemistry and Cytochemistry” Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
265 citations
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July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.