April 2023 in “Journal of Investigative Dermatology” Mutations in the SHH pathway in certain skin cells can cause skin tumors and abnormal hair growth.
24 citations
,
September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
February 2026 in “Journal of Cutaneous and Aesthetic Surgery” Ectopic acanthosis nigricans can occur at surgical sites due to skin graft mismatches.
13 citations
,
October 2020 in “Journal of Neural Transmission” CD34-positive cells help repair and form new blood vessels in salivary glands after radiation.
155 citations
,
December 2002 in “Journal of Investigative Dermatology” Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
June 2023 in “Research Square (Research Square)” Hair loss in male pattern baldness is linked to changes in immune cell behavior around hair follicles.
28 citations
,
July 2005 in “Journal of Investigative Dermatology” Sca-1+ cells in newborn mouse skin may become fat cells.
7 citations
,
January 1989 in “Archives of Dermatological Research” The side gland of Suncus murinus is a good model for studying human sebaceous glands.
24 citations
,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
6 citations
,
January 2017 in “Journal of toxicologic pathology” Rabbit skin with active hair growth shows thicker, redder areas due to larger, more numerous hair follicles and increased blood vessels.
July 2024 in “Indian Dermatology Online Journal” A benign tumor on the cheek, called trichoadenoma, should be surgically removed for cosmetic reasons.
17 citations
,
June 1997 in “Baillière's clinical obstetrics and gynaecology” Scientists now better understand how human hair growth is controlled, including the roles of specific genes and proteins.
June 2026 in “Journal of Investigative Dermatology” Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.
October 2021 in “Plastic and reconstructive surgery. Global open” Adipose-derived stem cells may help treat hair loss.
January 2004 in “Journal of Guangzhou University of Traditional Chinese Medicine” Androgen receptor abnormalities may contribute to hair loss in androgenetic alopecia.
4 citations
,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
14 citations
,
April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
18 citations
,
April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
51 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
32 citations
,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
4 citations
,
July 1979 in “Journal of the American Academy of Dermatology” The hair and oil glands react by changing structure when stressed.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” Surgical removal of an adrenal tumor resolved hormonal issues in a young woman.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
November 2022 in “Annals of Translational Medicine” Immune activities and specific genes are important in male pattern baldness.
10 citations
,
November 2007 in “Annals of Diagnostic Pathology” A rare benign tumor with hair follicle features was found on a man's trunk.
October 2017 in “Chinese Journal of Dermatology” 5 citations
,
August 2000 in “Archives of Pathology & Laboratory Medicine” The nodule on the woman's back was a benign hair follicle tumor, not cancer, but needed removal.
24 citations
,
April 2013 in “PLOS ONE” TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
5 citations
,
February 1981 in “Experientia” A new gene causes hairlessness and skin cysts in rats.
26 citations
,
April 2007 in “Journal of clinical oncology”