5 citations
,
June 2022 in “Biophysical Journal” TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.
43 citations
,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
28 citations
,
September 1998 in “Journal of Investigative Dermatology” Two distinct caspases in human skin help with cell death and skin formation.
2 citations
,
June 2018 in “International Journal of Pharmacological Research” Hutchinson-Gilford Progeria Syndrome caused rapid aging due to a genetic mutation, with treatments to manage symptoms.
1 citations
,
July 2022 in “Clinical, Cosmetic and Investigational Dermatology” Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.
Lysine carboxymethyl cysteinate (LCC) protects skin from UVB damage by activating autophagy.
December 2025 in “Advanced Healthcare Materials” The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
42 citations
,
July 2012 in “PLOS ONE” Estrogen can temporarily slow down hair growth but this can be reversed.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a new method to deliver molecules to hair follicles to manage hair growth without damaging surrounding skin.
12 citations
,
August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
665 citations
,
April 2016 in “Nature communications” Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
321 citations
,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
99 citations
,
January 2004 in “Progress in brain research” Neurotrophins are important for hair growth and could help treat hair loss.
55 citations
,
June 2012 in “Steroids” Testosterone affects vascular cells directly without converting to estradiol.
45 citations
,
October 2008 in “Cytokine & Growth Factor Reviews” Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
27 citations
,
May 2016 in “Integrative Cancer Therapies” Chrysin makes docetaxel more effective and reduces its side effects in lung cancer treatment.
19 citations
,
October 2008 in “Expert Review of Dermatology” EGF receptor is crucial for skin health and its inhibitors can cause skin rashes.
9 citations
,
March 2022 in “Antioxidants” Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
9 citations
,
November 2013 in “BMC Pharmacology and Toxicology” Suppressing eIF4E can prevent hair loss from chemotherapy.
8 citations
,
October 2019 in “The Journal of surgical research/Journal of surgical research” Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
6 citations
,
February 2022 in “Journal of immunology research” Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.
May 2026 in “International Journal of Molecular Sciences” Chemotherapy-induced hair loss may be linked to immune system changes, and certain treatments could help but need careful use.
December 2025 in “Clinical and Translational Science” EGFR inhibitors in breast cancer treatment can cause serious skin issues affecting patient quality of life.
November 2025 in “Biomedicines” Targeting pyroptosis may offer new treatments for alopecia areata, but more research is needed.
September 2025 in “Current Issues in Molecular Biology” IGF-1 can help regrow hair and may be a promising treatment for hair loss.
July 2025 in “World Journal of Stem Cells” Stem cell-derived exosomes could be a promising new treatment for hair regrowth.
Tofacitinib effectively regrows hair in alopecia universalis triggered by a virus.
April 2025 in “BMC Immunology” Targeting SIRT1 with antisense oligonucleotides could be a promising treatment for hair loss.
April 2025 in “International Journal of Dermatology” Prostaglandin E2 promotes skin cancer, but certain supplements and drugs may help reduce risk and improve treatment.