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Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

research The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages

36 citations , January 2007 in “Archives of Histology and Cytology”

Type IV collagen chains vary in different parts of human skin, with specific patterns linked to melanocytes.

Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream

34 citations , October 2014 in “European journal of pharmaceutics and biopharmaceutics”

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Curcuma Aeruginosa, A Novel Botanically Derived 5α-Reductase Inhibitor In The Treatment Of Male-Pattern Baldness: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

research Curcuma aeruginosa, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study

34 citations , July 2011 in “Journal of Dermatological Treatment”

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

research The Therapeutic Use of Topical Minoxidil

33 citations , April 1990 in “Dermatologic Clinics”

Minoxidil effectively treats hair loss, with better results in women.

research Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy

32 citations , August 2019 in “Nature Communications”

Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.

research Formulation and optimization of transfersome containing minoxidil and caffeine

32 citations , December 2017 in “Journal of Drug Delivery Science and Technology”

Minoxidil and caffeine in transfersomes improve hair growth treatment.

research The Additive Effects of Minoxidil and Retinol on Human Hair Growth in Vitro

32 citations , January 2007 in “Biological & Pharmaceutical Bulletin”

Minoxidil and retinol together help hair grow.

research Effect ofCitrullus colocynthisSchrad fruits on testosterone-induced alopecia

31 citations , September 2009 in “Natural Product Research”

Citrullus colocynthis fruit extract may effectively treat testosterone-related hair loss, similar to finasteride.

research Hair growth-promoting activities of chitosan and surface-deacetylated chitin nanofibers

30 citations , December 2018 in “International Journal of Biological Macromolecules”

Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.

research Microneedles mediated bioinspired lipid nanocarriers for targeted treatment of alopecia

28 citations , November 2020 in “Journal of Controlled Release”

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

research Applications and Risks of Nanomaterials Used in Regenerative Medicine, Delivery Systems, Theranostics, and Therapy

28 citations , January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems”

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

research The Latest Advance in Hair Regeneration Therapy Using Proteins Secreted by Adipose-Derived Stem Cells

28 citations , December 2012 in “The American Journal of Cosmetic Surgery”

Proteins from stem cells improved hair growth in patients with hair loss.

research Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5α-reductase inhibitor

28 citations , January 1991 in “Reproductive Toxicology”

Finasteride temporarily lowers male rat fertility without affecting libido.

research Hair growth promoting effect of white wax and policosanol from white wax on the mouse model of testosterone-induced hair loss

27 citations , February 2017 in “Biomedicine & Pharmacotherapy”

White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.

research Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege

27 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

Somatostatin may help protect hair follicles from immune attacks.

Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

research Skin-permeable liposome improved stability and permeability of bFGF against skin of mice with deep second degree scald to promote hair follicle neogenesis through inhibition of scar formation

26 citations , September 2018 in “Colloids and Surfaces B: Biointerfaces”

A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.

Development, Formulation, and Characterization of an Adapalene-Loaded Solid Lipid Microparticle Dispersion for Follicular Penetration

research Development, formulation, and characterization of an adapalene-loaded solid lipid microparticle dispersion for follicular penetration

26 citations , March 2014 in “International journal of pharmaceutics”

Researchers created a skin treatment that could effectively deliver medication into hair follicles.

research Fabrication of a 3D hair follicle‐like hydrogel by soft lithography

26 citations , March 2013 in “Journal of Biomedical Materials Research Part A”

Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.

research Measurement of hair growth

26 citations , March 1986 in “Clinical and Experimental Dermatology”

Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.

Preparation and Evaluation of a Multimodal Minoxidil Microemulsion Versus Minoxidil Alone in the Treatment of Androgenic Alopecia of Mixed Etiology: A Pilot Study

research Preparation and evaluation of a multimodal minoxidil microemulsion versus minoxidil alone in the treatment of androgenic alopecia of mixed etiology: a pilot study

24 citations , May 2013 in “Drug Design Development and Therapy”

Multimodal minoxidil microemulsion is more effective in treating hair loss than minoxidil alone.

research Minoxidil

24 citations , January 1993 in “Dermatologic Clinics”

Minoxidil effectively treats hair loss, works better for women, and requires consistent use.

research Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth

23 citations , January 2016 in “Theranostics”

Minoxidil-coated microbubbles with sonication effectively enhance hair growth.

research Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer

23 citations , January 2014 in “International Journal of Biological Sciences”

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.