3 citations
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March 2025 in “Science Advances” A specific DNA duplication in Polish chickens affects feather shape by altering gene expression.
86 citations
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April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
36 citations
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November 2019 in “Molecular biology and evolution” Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
330 citations
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December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
85 citations
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October 2006 in “Current opinion in cell biology” Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
38 citations
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November 2018 in “Scientific Reports” Bird scales evolved from feathers, not reptile scales.
22 citations
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December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
72 citations
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December 2018 in “Journal of Experimental Zoology Part B Molecular and Developmental Evolution” Corneous beta-proteins evolved uniquely in reptiles and birds, forming scales, claws, beaks, and feathers.
Pangolin scales evolved for protection, hardening with age, due to keratin gene diversification.
158 citations
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January 2009 in “The International Journal of Developmental Biology” Reptile scales help us understand the evolution of skin features like hair and feathers.
115 citations
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November 2008 in “Proceedings of the National Academy of Sciences” Reptiles have genes similar to hair proteins, suggesting hair's genetic origins predate mammals.
38 citations
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July 2004 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Reptilian scales, feathers, and hairs evolved from changes in skin cell interactions.
18 citations
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May 2023 in “Science Advances” Activating the sonic hedgehog pathway in chicken embryos can permanently change scales to feathers.
December 2024 in “Genome Biology and Evolution” Snakes and worm lizards lost claw proteins due to similar evolutionary changes.
20 citations
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December 2010 in “Journal of Morphology” Lizard claws have hair-like keratins similar to those in mammals.
33 citations
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October 2012 in “Journal of Morphology” Reptile skin hardens by layering beta-proteins on keratin.
23 citations
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January 2023 in “Journal of Developmental Biology” Reptile skin protects and prevents water loss, helping them adapt to land.
1 citations
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July 2023 in “Journal of developmental biology” Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
4 citations
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June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
47 citations
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July 2005 in “European Journal of Cell Biology” Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
19 citations
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March 2013 in “Biology Letters” Early tetrapod keratins evolved into toe pad proteins in amphibians and hair proteins in mammals.
May 2025 in “Journal of Developmental Biology” Jawless vertebrates have teeth proteins similar to those in mammalian hair and nails.
17 citations
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August 2014 in “The Anatomical Record” Scaffoldin helps form hard skin structures in chicken embryos.
68 citations
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April 2014 in “Journal of Investigative Dermatology” Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
133 citations
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February 2019 in “PLoS Biology” Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
151 citations
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November 2014 in “Annual Review of Animal Biosciences” Feathers are crucial for understanding bird evolution, development, and have inspired biomimetic research.
29 citations
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December 2004 in “Developmental biology” cDermo-1 causes dense skin, feathers, and scales in chickens.
26 citations
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August 1971 in “Journal of Morphology” Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.
44 citations
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May 2008 in “Acta Zoologica” Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
103 citations
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March 2011 in “PLoS Biology” Birds can lose neck feathers due to a genetic change that increases a gene's activity, helping them adapt to heat.