research Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome
Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
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930-960 / 1000+ resultsresearch Einfluss von Melatonin auf die Physiologie des Haares
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
research The Role of Probiotics and Synbiotics on Hirsutism
Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
research Androgens in cervical cancer: Their role in epidemiology and biology
Androgens increase cervical cancer risk and affect its development.
research Modelling Human Hair Follicles—Lessons from Animal Models and Beyond
Improving human hair follicle models is crucial for better hair loss treatments.
research Apoptosis in Hair and Skin: A Review
The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
research Microglia: sculptors of the polycystic ovary syndrome (PCOS)-like brain?
Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
research 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.
research Comparative proteomic analysis of male and female androgenetic alopecia: elucidating gender-specific molecular patterns
Male and female pattern hair loss have different molecular pathways, suggesting unique treatment targets for each sex.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology
Environmental pollutants can damage hair health and cause hair loss.
research Androgens in postmenopausal women
Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
research Exploring the impact of ovariectomy on hair growth: can ovariectomized mouse serve as a model for investigating female pattern hair loss in humans?
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research 17α‐estradiol induces aromatase activity in intact human anagen hair follicles ex vivo
17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
research Gene-wide association study between the aromatase gene (CYP19A1) and female pattern hair loss
Aromatase gene variation may increase female hair loss risk.
research Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin
Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
research Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5α-reductase inhibitor
Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.
research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors
Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.
research Aromatase inhibitor therapy and hair loss among breast cancer survivors
Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.
research Aromatase inhibitors induce ‘male pattern hair loss’ in women?
Aromatase inhibitors cause male pattern hair loss in women.
research Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss
No link found between aromatase gene and female hair loss.
research Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats
Inhibiting certain enzymes made female rats more sensitive to low-level pain.
research Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice
Letrozole reduces seizures but not brain damage in mice.
research A Phase II Study of Vaginal Testosterone Cream (TEST) vs. Estring for Vaginal Dryness or Decreased Libido in Women with Early Stage Breast Cancer (BC) Treated with Aromatase Inhibitors (AIs).
Both vaginal testosterone cream and Estring effectively manage vaginal dryness in women with early-stage breast cancer on aromatase inhibitors.
research CDK4/6 plus aromatase inhibitor-induced alopecia in breast cancer patients.
Some breast cancer treatments cause hair loss similar to male pattern baldness, which can be improved with minoxidil.
research Adverse events associated with aromatase inhibitors: an analysis of real-world datasets and drug-gene interaction network
Aromatase inhibitors can cause various adverse reactions, so monitoring is crucial.
research Aromatase inhibitor–induced hair loss in two adolescents
Two teenage boys lost hair after taking a drug for growth, which was not a known side effect for kids.
research Inibição seletiva da 5α-redutase e preservação da aromatase no transplante capilar
A balanced approach using dutasteride and Serenoa repens can improve hair transplant success by protecting follicles and minimizing side effects.