research Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
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research Beyond testosterone cypionate: evidence behind the use of nandrolone in male health and wellness
Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
research The Safety of Testosterone Therapy in Women
Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
research Oligomenorrhoea in Exercising Women
Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.
research The effects of oestrogens on linear bone growth
Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage—Animal, Experimental Study
Finasteride may cause kidney damage.
research Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research The Diagnosis and Management of Hirsutism
The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Outcome Disparities Among Men and Women With COVID-19: An Analysis of the New York City Population Cohort
Men had worse COVID-19 outcomes than women in New York City.
research Indirect clinical markers for the detection of anabolic steroid abuse beyond the conventional doping control in athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research A patient with combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2
A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.
research Testosterone Treatment in Women – An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research Treatment of hyperandrogenism in women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Penile vascular abnormalities in young men with persistent side effects after finasteride use for the treatment of androgenic alopecia
Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
research Post-finasteride syndrome – does it really exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research Androgen receptor CAG repeat length is associated with ovarian reserve but not with ovarian response
The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.
research Safety and efficacy of transdermal testosterone for treatment of hypoactive sexual desire disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
research Drug safety evaluation of exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Bone density is normal in male rats treated with finasteride
Finasteride doesn't affect bone density in male rats.
research Polycystic ovarian syndrome and associated hirsutism in the adolescent
Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.
research Transmasculine Hormone Therapy
Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
research Effect of finasteride on ovulation induction in nonresponder (hyperandrogenic) polycystic ovary syndrome (PCOS) women
Finasteride helps induce ovulation in nonresponder PCOS women.
research Association of Polycystic Ovarian Syndrome (PCOS) With Vaginal Microbiome Dysbiosis: A Scoping Review
PCOS is linked to changes in vaginal bacteria, with fewer good bacteria and more harmful ones.
research The impact of exogenous vitamin D on thyroid autoimmunity in euthyroid men with autoimmune thyroiditis and early-onset androgenic alopecia
Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
research Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men
Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
research PCOS and Obesity: Contraception Challenges
Low-dose ethinyl estradiol and LNG-IUD are safer contraception options for obese women with PCOS.
research Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials
Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.