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540-570 / 1000+ resultsresearch Studies of androgen metabolism and action in cultured hair and skin cells
Androgens don't directly affect hair cell growth or protein production.
research Effects of Intramuscular Testosterone Undecanoate on Body Composition and Bone Mineral Density in Female-to-Male Transsexuals
Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.
research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Simultaneous determination of androgens and prostaglandins in human urine using ultra-high-performance liquid chromatography–tandem mass spectrometry
Researchers developed a quick and accurate method to measure hormones in urine, confirming a baldness treatment's effectiveness without altering hormone levels.
research In silico screening of effective inhibitor of 5α-reductase type 1 for androgenic alopecia treatment
β-sitosterol and brassicasterol may help treat hair loss.
research The role of androgen therapy
Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.
research Hormonal Treatment Strategies Tailored to Non-Binary Transgender Individuals
Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.
research Sexual dysfunction with 5-alpha-reductase inhibitor therapy for androgenetic alopecia: a global propensity score matched retrospective cohort study
Taking medication for hair loss might cause sexual problems.
research News & Notes
Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
research Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
research Antiandrogens as Therapies for COVID-19: A Systematic Review
Antiandrogens don't help with COVID-19 and aren't recommended.
research The feasibility of quantitative analysis of androgen metabolism by use of single dermal papillae from human hair follicles
Using single dermal papillae is unreliable for analyzing androgen metabolism in hair follicles.
research Serum lipidomic changes and sex differences in androgenetic alopecia
People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.
research Finasteride/testosterone undecanoate
Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.
research Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells
New compounds may help treat prostate cancer by reducing cell growth.
research Hyperandrogenismus, adrenale Dysfunktion und Hirsutismus
Excessive male hormones in women cause symptoms like unwanted hair growth, and treatment requires careful medical evaluation.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Role of Androgen Receptor in Hypothalamic Regulation of Metabolism and Reproduction
Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.
research Simultaneous determination of androgens and prostaglandins in human urine using ultra-high-performance liquid chromatography–tandem mass spectrometry
Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.
research SUN-049 Male Pattern Baldness and Waist-Hip Ratio as Markers of Arterial Stiffness in Transgender Men Undergoing Long-Term Testosterone Therapy
Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
research The stimulation of hair growth in the flank organs of female hamsters by subcutaneous testosterone propionate and its inhibition by topical cyproterone acetate: dose-response studies
Testosterone increases hamster hair growth; cyproterone acetate reduces it.
research Serum Androgen Bioactivity in Adolescence: A Longitudinal Study of Boys with Constitutional Delay of Puberty
Testosterone and letrozole treatment speeds up puberty in boys with delayed development.
research The use of phytochemicals and other natural materials in the treatment of androgenetic alopecia
Natural substances like caffeine and rosemary oil may help hair growth, but more research is needed.
research The evaluation and treatment of androgen excess
High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
research C19and C215β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research 341 ANDROGENETIC ALOPECIA AT VARIOUS AGES AND PROSTATE CANCER RISK IN AN EQUAL ACCESS MULTIETHNIC CASE CONTROL SERIES OF VETERANS
Early baldness increases prostate cancer risk, radiotherapy and surgery have similar second cancer rates, and ALA may reduce prostate cancer risk.
research The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency.
Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.
research The Rise in Adrenal Androgen Biosynthesis: Adrenarche
Adrenarche increases adrenal androgens around age 6, affecting hair growth and development.