153 citations
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November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
4 citations
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July 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.
196 citations
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May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
18 citations
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December 2005 in “Journal of Medicinal Chemistry” A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
6 citations
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August 2020 in “International Research Journal on Advanced Science Hub” The niosomal gel effectively delivers testosterone through the skin with fewer side effects.
120 citations
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April 2019 in “The Journal of clinical investigation/The journal of clinical investigation” Both estrogens and androgens are important for health in both males and females.
January 2021 in “Journal of The European Academy of Dermatology and Venereology” Men with hair loss who take a certain type of medication may experience fewer COVID-19 symptoms.
309 citations
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June 2001 in “Molecular and Cellular Endocrinology” Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
23 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
20 citations
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January 2019 in “Journal of dermatological science” Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
July 2022 in “World Journal of Advanced Research and Reviews” Piptadeniastrum africanum and Cordia plathytyrsa can increase testosterone without major metabolic changes, but may affect triglycerides and creatinine.
20 citations
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March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
research Acne
81 citations
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January 2002 in “American journal of clinical dermatology” Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
1 citations
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September 2010 in “UEF eRepo (University of Eastern Finland)” Androgen receptors help prostate cancer cells grow and resist drugs.
1 citations
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October 2018 in “InTech eBooks” Ethosomes are a promising method for treating hair loss by delivering drugs directly to the scalp.
1 citations
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November 1989 in “PubMed” Male-pattern baldness is a natural process with unclear causes, and while Minoxidil can help, the results often aren't satisfactory.
1 citations
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January 2010 in “Endocrine abstracts”
150 citations
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February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Antiandrogens are somewhat effective in reducing excessive hair growth in women.
October 2025 in “Scientific Reports” AR gene variations don't affect aging markers in men.
15 citations
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May 2009 in “Steroids” Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
36 citations
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October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
3 citations
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October 2024 in “The Journal of Clinical Endocrinology & Metabolism” Potential androgen excess signs vary by demographics and health, needing inclusive evaluation.
Hormones beyond androgens may cause acne and hair loss.
165 citations
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December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
2 citations
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December 2020 in “Phytomedicine plus” Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.
9 citations
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April 2021 in “Expert opinion on pharmacotherapy” Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
Androgen receptors significantly affect hair loss in women with androgenetic alopecia.
2 citations
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May 2012 in “Indian drugs” Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.