Search

everythinglearnresearchcommunity

for

Search:↓

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Dutasteride effectively treats benign prostatic hyperplasia but isn't approved for preventing prostate cancer.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

Long-term use of dutasteride can cause permanent erectile dysfunction in rats.

IVL-DrugFluidic® can mass-produce high-quality, long-acting injectable drug microspheres, improving patient compliance and reducing side effects.

Dutasteride potentially improves cell survival and reduces retinal damage in retinitis pigmentosa.

Finasteride improves heart function and repairs damage after heart attack in mice.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

Finasteride and dutasteride may cause macular abnormalities.

imTA and pulse therapy are effective for alopecia areata with manageable side effects, but relapse rates need improvement.

A woman developed swelling in her body after taking low-dose oral minoxidil for hair loss, but it resolved after stopping the medication.

A new microneedle system effectively delivers a vasodilator to hair follicles, promoting hair growth better than current treatments.

Minoxidil effectively lowers severe high blood pressure long-term but isn't for routine use.

Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Digoxin is linked to a higher risk of anemia in patients with atrial fibrillation and heart failure.

Taking dutasteride for one month before prostate surgery can reduce bleeding.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Doxazosin alone or combined with finasteride improves prostate symptoms better than finasteride alone, without extra benefits.

The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.

5α-reductase inhibitors help treat prostate enlargement and hair loss but may cause side effects, requiring careful use.

Minoxidil can cause severe body swelling and fluid buildup, which improves after stopping the drug and using diuretics.

The FDA did not approve a testosterone drug because of safety concerns.

Dutasteride effectively treats hair loss and prostate issues.

Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.