research Left Anterior Descendent Coronary Artery Fistula to Main Pulmonary Artery with Triple Vessel Disease:A Report of Two Cases
Two patients with heart issues had successful surgeries and improved symptoms.
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research Ischemic onycholysis of the hands
A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.
research Intraretinal variation in disease severity in the Oat mouse model of gyrate atrophy
The Oat mouse model shows mild retinal degeneration, useful for testing treatments.
research Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing
Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
research A perspective on small molecules targeting the renin–angiotensin–aldosterone system and their utility in cardiovascular diseases: exploring the structural insights for rational drug discovery and development
Targeting the RAAS with small molecules can improve cardiovascular disease treatments.
research Is the severity of alopecia areata associated with arterial stiffness?
Severe alopecia areata may increase the risk of heart-related diseases.
research Role of boundary conditions in an experimental model of epithelial wound healing
Mast cells and VEGF contribute to post-surgery adhesions, and blocking VEGF can reduce these adhesions; also, certain factors affect wound healing and fetal skin heals differently with age.
research Corrigendum to “Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice” Journal of Molecular and Cellular Cardiology 122 (2018) 114–124
Finasteride improves heart function and repairs damage after heart attack in mice.
research Senescence-induced reparative fibroblasts enable scarless wound healing in aged murine skin.
Older mice heal wounds without scars due to special fibroblasts.
research Human CD133 + Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling
CD133+ cells help heal diabetic ulcers by promoting blood vessel growth and activating Wnt signaling.
research Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation
Adult fibroblasts help heart cells mature and improve heart function.
research Evaluation of Anthropometric Measurements, Arterial Stiffness and ECG Parameters in Alopecia Areata Patients
Alopecia areata may be linked to changes in body fat but not to heart or artery issues.
research Hair trace elementary profiles in aging rodents and primates: links to altered cell homeodynamics and disease
research Dihydrotestosterone induces arterial stiffening in female mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Whole Body and Regional Hemodynamic Effects of Minoxidil in the Conscious Dog
Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
research A Comparative Study of Minoxidil-Induced Myocardial Lesions in Beagle Dogs and Miniature Swine
A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
research The Therapeutic Use of Topical Minoxidil
Minoxidil effectively treats hair loss, with better results in women.
research Solubility of Minoxidil in Methanol, Ethanol, 1-Propanol, 2-Propanol, 1-Butanol, and Water from (278.15 to 333.15) K
Minoxidil dissolves best in methanol and least in water.
research Intravascular and Interstitial Fluid Dynamics in Rats Treated with Minoxidil
Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
research USO DO MINOXIDIL PARA TRATAMENTO DE ALOPECIA ANDROGENÉTICA
The document reviews the use of minoxidil for treating androgenetic alopecia (AGA), focusing on its efficacy and safety in women. It analyzes 8 articles and finds that low-dose oral minoxidil (0.25 to 5 mg/day) is effective and generally well-tolerated, with mild side effects like hypertrichosis. Oral minoxidil may be as effective as topical solutions, offering a convenient alternative for those who do not respond well to topical treatments. A study showed that 70% of women with AGA improved with 1 mg oral minoxidil compared to 46% with 5% topical minoxidil. Despite not being FDA-approved, oral minoxidil shows promise, but further studies are needed to determine the optimal dosage and long-term safety.
research The Effects of Botulinum Toxin on Vascular Diameter: A Preliminary Report
Botulinum toxin type A may widen certain arteries, but more research is needed.
research Blocking α1‐integrin reverts the adhesive phenotype of adult fibroblasts towards a foetal‐like migratory phenotype
Blocking α1-integrin makes adult fibroblasts more like foetal ones, improving their movement and aiding wound healing.
research Three-dimensional microvascular organization around hair follicles as revealed by FITC-dextran injection method
research 574 Three-dimensional culture of dermal papilla cells improves their in vitro angiogenic activity
Growing dermal papilla cells in 3D improves their ability to help form new blood vessels.
research Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting
Using adipose tissue-derived fragments improves early skin graft success.
research Inflammation as a Modifiable Driver of Ischemic Heart Disease: Mechanisms, Clinical Risks, and Evolving Therapeutic Options
Inflammation is a key factor in heart disease and targeting it can reduce heart problems.
research APPLICATION OF ACELLULAR GRAFTS FOR EXTENSIVE SKIN DEFECTS – A REVIEW
Granulation and epithelialization are crucial for healing large skin wounds.
research Cardiac morphologic alterations in acute minoxidil cardiotoxicity in miniature swine
research Biologically Driven Innovations in Aesthetic Surgery: Advances in Regenerative and Cellular Therapies
Regenerative therapies are improving aesthetic surgery by enhancing tissue quality and healing.