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The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Spironolactone may help reduce hair loss in androgenic alopecia.

The compound 4c showed strong potential as an anticancer agent.

Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.

Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.

Alkylating agents can kill cancer cells but may cause skin and allergic reactions.

Ficus platyphylla leaf extract is likely safe in high doses, with minor temporary side effects.

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

Five existing drugs may help fight Swine Acute Diarrhea Syndrome Coronavirus.

Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.

Ritlecitinib is effective and safe for treating alopecia areata, promoting significant hair regrowth.

Monitor for early signs of azathioprine toxicity and check blood counts regularly.

Low-dose topical alpha-terthienyl may be a safer option for treating skin conditions with light therapy.

Alopecia areata patients are more likely to have thyroid disorders than healthy individuals.

Excessive iodine from a cystic fibrosis supplement can cause hypothyroidism.

Ritlecitinib is the first FDA-approved pill for treating significant hair loss in alopecia areata patients aged 12 and up.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

Lamotrigine can cause hair loss in some patients.

Six African American women experienced hair loss after switching to a new HIV medication.

Compound 3 protects the heart from damage by activating A1-adenosine receptors.

Many drugs, not just chemotherapy, can cause reversible hair loss.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Higher doses of 5α-reductase inhibitors may lower mortality risk, but low doses increase it.

Valproate can cause brain swelling with high ammonia levels, possibly underreported, especially in psychiatric patients.

Ritlecitinib is effective and safe for hair regrowth in Asian patients with alopecia areata.