research A new target for squamous cell skin cancer?
Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
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research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia
Finasteride side effects in young men may be linked to specific gene variations.
research 안드로겐성 탈모증 환자에서 폴리감마 글루탐산 하이드로겔 나노입자에 포집한 혼합복합발효추출물 도포제의 임상시험
The solution increased hair density safely and effectively for hair loss.
research CircAGK regulates high dihydrotestosterone‐induced apoptosis in DPCs through the miR‐3180‐5p/BAX axis
CircAGK affects cell death in hair cells by controlling the miR-3180-5p/BAX pathway, which can lead to hair loss.
research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study.
Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
research Decision letter: Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
research A Prospective Double-Blind Placebo Controlled Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia
Platelet-rich plasma treatment significantly improved hair density and regrowth in both men and women suffering from pattern hair loss, with even better results when combined with certain medications.
research Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C
Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.
research Additional Intraoperative Autologous-Derived Platelet-Rich Stroma to Transanal Flap Repair for the Treatment of Cryptoglandular Transsphincteric Fistulas in a Tertiary Referral Center: Long-Term Outcomes of a Prospective Pilot Study
Combining PRS with TAFR is promising for treating complex fistulas, with most patients achieving long-term healing.
research Prevalence of MMP-1 rs1799750 Polymorphism in Androgenetic Alopecia: A Cross-Sectional Study in an Indonesia Population
There is no significant link between the MMP-1 rs1799750 polymorphism and androgenetic alopecia in the Indonesian population.
research Utility of platelet-rich plasma in aesthetics
PRP is popular in aesthetic treatments but its effectiveness and safety are still questioned.
research Síndrome de ovario poliquístico: la distancia anogenital como marcador del entorno androgénico prenatal y revisión y comparación de los criterios diagnósticos
Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.
research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice
research Identification of a recurrent nonsense mutation in HR gene responsible for atrichia with papular lesions in two Kashmiri families
A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.
research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration
Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
research 43399 Growing uses of PRP: an evaluation of hair growth in cicatricial alopecia
PRP's benefits for treating scarring hair loss are still uncertain.
research 573 A review of the use of platelet rich plasma for the treatment of androgenic alopecia
Platelet Rich Plasma can potentially help in restoring hair loss, but more research with larger groups is needed to confirm its effectiveness and standardize its use.
research Characterization of distinct microbiota associated with androgenetic alopecia patients treated and untreated with platelet‐rich plasma (PRP)
PRP treatment helps hair growth and rebalances scalp bacteria in androgenetic alopecia patients.
research Expression of MsPG3‐GFP fusions in Medicago truncatula‘hairy roots’ reveals preferential tip localization of the protein in root hairs
MsPG3 protein gathers at root hair tips, aiding growth.
research Local Injection versus Topical Microneedling of Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review
PRP with microneedling works better than injection for hair loss treatment.
research A Case of Androgenetic Alopecia (AGA) Successfully Treated with Combined Treatment of Basalt Stone Treatment and Placenta Extract: A Case Report
Hair thinning improved with basalt stone and placenta extract treatment but recurred when paused.
research The effect of platelet‐rich plasma injection in the treatment of androgenetic alopecia
PRP injections improve hair thickness and density in hair loss, but more research needed.
research Androgenetic Alopecia: Narrative Review of Current Therapies and Proposal of a Practical Algorithm for Pharmacological Treatment
Androgenetic alopecia (AGA) affects a significant portion of the population, with 80% of White men and up to 40% of women experiencing it by age 70, impacting mental health and quality of life. Current treatments approved by American and European agencies are effective and safe, but other therapies also show promise despite lacking randomized clinical trials. This review summarizes available treatments and proposes a practical management algorithm to assist clinicians in choosing the most suitable therapy based on clinical experience and disease severity.
research Exome-wide age-of-onset analysis reveals exonic variants in ERN1, TACR3 and SPPL2C associated with Alzheimer’s disease
Certain genetic variants in ERN1, TACR3, and SPPL2C are linked to when Alzheimer's disease starts.
research 498 A Multi-Omics Approach to create a Human Hair Atlas for healthy and AGA models
The research aims to better understand hair follicle regulation and find new treatments for hair loss.
research ISID1394 - Long non-coding RNA AL136131.3 inhibits hair growth through mediating glycolysis in androgenetic alopecia
The RNA AL136131.3 slows down hair growth and speeds up hair loss by affecting sugar breakdown in hair follicles.
research 医療機関における男性型脱毛症（AGA）診療に対する受診満足度調査
Patients were generally dissatisfied with over-the-counter hair growth products but wanted to consult doctors for hair loss treatment.
research Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
PRP injections significantly increased hair count and density with less pain.
research Comparison Of Single And Double-Spin Platelet- Rich Plasma Therapy For Treating Androgenetic Alopecia In Males: A Double-Blinded Randomized Controlled Trial
Double-spin PRP is more effective for treating male pattern baldness.