research 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat
5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.
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research The role of activins and follistatins in skin and hair follicle development and function
Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
research Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights
Changes in scalp microbes may contribute to hair loss, suggesting new treatment options.
research Skin signs of nutritional disorders.
Malnutrition causes skin changes due to nutrient deficiencies.
research Investigating Biochemical Biomarkers in Telogen Effluvium Post-COVID-19 Patients: A Retrospective Cohort Study
COVID-19 can cause hair loss due to stress, with inflammation markers like D-dimer levels playing a role.
research Hazards of Topical Mitotic Blocking Agents
Topical mitotic blocking agents like colchicine can be dangerous and potentially fatal, and hair loss from rapid weight loss is due to low protein, not the speed of weight loss.
research Antigen presenting cells in the skin of a patient with hair loss and systemic lupus erythematosus.
Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
research Re: Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia
Early hair loss may indicate future prostate issues.
research Computational Drug Discovery in Chemotherapy-induced Alopecia via Text Mining and Biomedical Databases
Computational tools identified 29 drugs that could potentially target 19 genes involved in chemotherapy-induced hair loss, which could lead to more effective treatments.
research Genetics of Structural Hair Disorders
The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
research 441 RPGRIP1L facilitates desmosomal adhesion through suppressing PKCβII-mediated desmoglein endocytosis: Implication in pemphigus
RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.
research 男性型脱毛症の原因についての手がかり
A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.
research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Both gene and non-gene areas of DNA evolved to make some mammals hairless.
research Activating Wnt/β-catenin signaling pathway for disease therapy: Challenges and opportunities
Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
research Interactions of the Vitamin D Receptor with the Corepressor Hairless
Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
research GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing
GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
research Special Biochemical Features of the Hair Follicle
Hair follicles have unique proteins that vary by species and are influenced by nutrition.
research Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Identification of Candidate Genes for Min Pig Villi Hair Traits by Genome-Wide Association of Copy Number Variation
Researchers found genes that may explain why some pigs grow winter hair, which could help breed cold-resistant pigs.
research 1341 Possible role of mTOR signaling pathway in radiation dermatitis
The mTOR signaling pathway might play a role in radiation dermatitis, but more research is needed.
research Clinical analysis of rash in systemic lupus erythematosus
Rash in SLE patients indicates more severe disease.
research Variant PADI3 in Central Centrifugal Cicatricial Alopecia
Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.
research The proteomic profile of hair damage
Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
research How different is human hair? A critical appraisal of the reported differences in global hair fibre characteristics and properties towards defining a more relevant framework for hair type classification
Human hair varies widely and should be classified by curl type rather than race.
research Editor's evaluation: Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
research 301 Association between Hair Proliferation and Flavonoid Silibinin in Human Dermal Papilla Cells
Silibinin may help promote hair growth and treat hair loss.
research Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks
Hair loss in male pattern baldness is linked to changes in specific genes and proteins that affect hair growth and scalp health.
research A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia
The study identified 12 potential biomarkers for hair loss and how they affect hair growth.
research Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival
The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
research The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor
The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.