July 2016 in “Journal of Investigative Dermatology” R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.
Activin A and Follistatin affect how mouse hair follicles grow.
7 citations
,
January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
10 citations
,
September 2021 in “The FASEB Journal” ACKR2 helps prevent skin scarring and hair loss by controlling inflammation.
301 citations
,
May 1998 in “Genes & Development” Ets2 gene is crucial for placental development in mice.
59 citations
,
November 2011 in “Development” Trps1 is essential for proper hair follicle development.
11 citations
,
January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
110 citations
,
April 2009 in “Cell Motility and the Cytoskeleton” β‐thymosins, especially thymosin β4, help in heart protection, wound healing, and hair growth by stabilizing actin in cells.
Raptor and Rictor have stable expression in hair cycles, with Raptor marking stem cells and Rictor involved in hair shaft formation.
1 citations
,
January 2012 The CRABP I gene in cashmere goats is highly conserved but has unique features at specific amino sites.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
11 citations
,
January 1996 in “PubMed” Imaging living plant cells shows dynamic changes in actin and endoplasmic reticulum linked to root hair growth.
The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.
51 citations
,
February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
January 2023 in “Methods in molecular biology” ROP GTPase helps control the growth of pollen tubes and root hairs by managing cell structure and movement.
1 citations
,
January 2004 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” SPARC likely aids in tissue remodeling during the hair cycle, not in starting new hair growth phases.
38 citations
,
September 2011 in “PLOS ONE” Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.
October 2014 in “Cancer research” Blocking mTORC1 reduces skin tumor growth in mice.
Thymosin β4 helps with healing, inflammation, and organ protection.
December 2022 in “Frontiers in plant science” CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.
56 citations
,
December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
3 citations
,
February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine” A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
14 citations
,
April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
January 2011 in “Anhui nongye kexue” The vector successfully directed specific gene expression in hair follicles.
52 citations
,
July 2011 in “PubMed” TRPS1 is crucial for bone, kidney, and hair follicle development.
11 citations
,
December 2017 in “Orphanet Journal of Rare Diseases” A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.
384 citations
,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
24 citations
,
May 2009 in “The FASEB Journal” Akt2 and SGK3 are both important for normal hair growth and development.
11 citations
,
June 2017 in “Journal of cell science” AGD1's PH domain is essential for its role in root hair growth and polarity.
70 citations
,
August 2006 in “Cancer Research” AP-1 controls tumor cell type by affecting key signaling pathways.