June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” People with moderate or severe hair loss are at a higher risk of dying from diabetes and heart disease.
January 1995 in “Adolescent and pediatric gynecology” Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
5 citations
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March 2023 in “International Journal of Trichology” Alopecia areata patients may have higher cardiovascular risk factors, so screening for metabolic syndrome components is suggested.
April 2012 in “The Journal of Urology” Early baldness increases prostate cancer risk, radiotherapy and surgery have similar second cancer rates, and ALA may reduce prostate cancer risk.
Oxidative stress is linked to mild patchy alopecia areata.
34 citations
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July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
3 citations
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July 2024 in “Journal of Vascular Diseases” Ischemia-modified albumin can help diagnose ischemic conditions early, but better detection methods are needed.
Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.
May 2023 in “Arteriosclerosis, thrombosis, and vascular biology” Finasteride may slow down heart disease by lowering cholesterol and reducing inflammation.
September 2024 in “Cureus” A new method improves platelet testing for heart disease patients.
Men with male pattern baldness are more likely to have heart disease risk factors, so they should get heart screenings early.
3 citations
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September 2024 in “Experimental Dermatology” IL-18 levels are higher in hidradenitis suppurativa patients and may indicate disease severity.
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
13 citations
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September 2013 in “Steroids” The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
1 citations
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December 2017 in “Turkderm” People with a family history of hair loss are more likely to experience it, and the severity of hair loss is linked to insulin resistance. The connection between early hair loss and oxidative stress needs more investigation.
October 2017 in “Indian heart journal” Obesity is an independent risk factor for early coronary artery disease (CAD) and its severity is not affected by age.
January 2016 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” Insulin resistance varies among PCOS types, and simple math tools can help identify it early.
January 2019 in “Indian Journal of Public Health Research and Development”
2 citations
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September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
6 citations
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October 2021 in “Biomedical Research and Therapy” Alopecia areata patients have higher levels of IL-6 and TNF-α.
4 citations
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December 2021 in “Clinical and Experimental Reproductive Medicine” Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.
9 citations
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October 2014 in “Experimental and Clinical Endocrinology & Diabetes” Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.
June 2026 in “Archives of Dermatological Research” PCAT1 and HOTAIR levels are lower in people with androgenic alopecia.
2 citations
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January 2013 in “Türkiye klinikleri tıp bilimleri dergisi” The study suggests using a score of 11 on the mFG scale to diagnose hirsutism in Turkish women, with adjustments for age, skin type, and family history.
8 citations
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April 1991 in “European journal of endocrinology” 3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.
15 citations
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July 2012 in “Biological trace element research” Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
37 citations
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January 2005 in “Dermatology Online Journal” Women under 55 with hair loss (AGA) may have a higher risk of heart disease (CAD).
4 citations
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July 2023 in “Analytical and Bioanalytical Chemistry” 50 citations
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August 2019 in “Cell Communication and Signaling” NFAT5 triggers atherosclerosis under stress by activating inflammation in blood vessels.