research IL-17 axis is a significant driver of skin inflammation in Card14 mutant pityriasis rubra pilaris model mice
Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
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810-840 / 1000+ results research The first broad replication study of SNPs and a pilot genome‐wide association study for androgenetic alopecia in Asian populations
Two specific genetic markers increase the risk of hair loss in Asian populations.
research Novel Missense Mutation in the P-Box of Androgen Receptor in a Patient with Androgen Insensitivity Syndrome
A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.
research Lack of androgen receptor transcriptional activity in human keratinocytes
Human keratinocytes do not naturally respond to androgens.
research Distribution of P2X3‐immunoreactive fibers in hairy and glabrous skin of the rat
P2X3-IR fibers are widespread in rat skin and likely help detect pain.
research 570 Targeting phosphodiesterase 8A (PDE8A) to boost adipogenesis and hair regeneration
Inhibiting PDE8A may help treat hair loss by boosting fat cell growth and hair regeneration.
research ‘Atrichosis’, a new hairless gene with cyst formation in rats
A new gene causes hairlessness and skin cysts in rats.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Platelet-rich plasma for androgenic alopecia treatment: A comprehensive review
PRP shows promise for treating hair loss but needs more research.
research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
research Overexpression of alkaline phosphatase improves the hair-inductive capacity of cultured human dermal papilla spheres
Increasing alkaline phosphatase in human skin cells helps to grow more hair.
research Greater Trochanteric Pain Syndrome and the Efficacy of Platelet-Rich Plasma Injections: A Systematic Review
PRP injections help relieve hip pain in most cases.
research STUB1 mutations in autosomal recessive ataxias – evidence for mutation-specific clinical heterogeneity
Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.
research MODERN POSSIBILITIES OF CLINICAL APPLICATION OF PLATELET-RICH PLASMA
Platelet-rich plasma therapy is widely used in medicine for its effectiveness and safety, but more research is needed to fully understand its potential.
research Práticas de produção, armazenamento e utilização do plasma rico em plaquetas e produtos relacionados no Brasil: estudo transversal
Regulatory measures are needed to ensure safe production and use of platelet concentrates in Brazil.
research Ponatinib-induced pityriasis rubra pilaris-like adnexal dysmaturation: A case report
Ponatinib can cause a rare skin reaction that resolves with topical treatment and temporary drug discontinuation.
research Plasma rico en plaquetas en pacientes con trasplante capilar. Revisión de la literatura
PRP may help improve hair transplant results.
research Plasma rico en plaquetas en pacientes con trasplante capilar. Revisión de la literatura
PRP may help improve hair transplant results.
research Comparing Single Spin versus Double Spin Techniques of Platelet Rich Plasma Preparation in Treating Male Androgenetic Alopecia: A Prospective Study
Both single and double spin PRP methods effectively treat male hair loss, but single spin is easier and cheaper.
research Characterization of distinct microbiota associated with androgenetic alopecia patients treated and untreated with platelet‐rich plasma (PRP)
PRP treatment helps hair growth and rebalances scalp bacteria in androgenetic alopecia patients.
research The effect of autologous activated platelet-rich plasma injection on female pattern hair loss: A randomized placebo-controlled study
PRP injections improve hair density and thickness in women with hair loss.
research A Brief Study Examining the Variability of PRP with Different Preparation Systems
Different PRP systems produce varying levels of platelet concentrations.
research Arabinogalactan proteins are involved in root hair development in barley
Certain proteins are essential for the growth of root hairs in barley.
research AP collagen peptides (APCPs ) promote hair growth by activating the GSK ‐3β/β‐catenin pathway and improve hair condition
AP collagen peptides help hair grow and improve hair health.
research Cell wall-associated ROOT HAIR SPECIFIC 10, a proline-rich receptor-like kinase, is a negative modulator of Arabidopsis root hair growth
ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
research Response to: “Minimum requirements for reporting clinical trials evaluating the therapeutic potential of platelet-rich plasma”
The authors agree that standardizing how PRP methods are reported could help compare results, but note that the link between PRP's contents and hair growth is unclear, and recommend avoiding split-scalp designs in future trials.
research Modulation of Androgen Receptor Transcriptional Activity
Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.
research The mechanism of activated platelet‐rich plasma supernatant promotion of hair growth by cultured dermal papilla cells
Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.
research p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen)
Blocking a specific receptor slows down hair loss in mice.
research Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism
Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.