research Baricitinib for the Treatment of Alopecia Areata
Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.
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research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Forsythiaside A Activates AMP-Activated Protein Kinase and Regulates Oxidative Stress via Nrf2 Signaling
Forsythiaside A helps protect cells and liver from damage by reducing oxidative stress and boosting antioxidants.
research Synthesis of 5α-Reductase Special inhibitor Finasteride
Finasteride is made through a series of chemical reactions starting from a specific intermediate compound.
research Frontal fibrosing alopecia in Asians: a retrospective clinical study
The study concluded that combination therapy with topical corticosteroids and hydroxychloroquine or finasteride is effective in treating Frontal fibrosing alopecia in Asians.
research New Synthesis of Finasteride
A new method to make Finasteride is more cost-effective and yields 16%.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research The Diverse Experiences and Challenges of Individuals With Alopecia Areata: Survey Results From Finland
Alopecia areata greatly affects quality of life, with many experiencing mental health issues and lacking professional support.
research Penile vascular abnormalities in young men with persistent side effects after finasteride use for the treatment of androgenic alopecia
Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
research A comparison of the relative efficacy of antiandrogens for the treatment of acne in hyperandrogenic women
Flutamide and CPA are more effective than finasteride for treating acne in hyperandrogenic women.
research 331 An open label clinical trial of the JAK inhibitor tofacitinib for alopecia areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Lack of efficacy of apremilast in 9 patients with severe alopecia areata
Apremilast did not work for treating severe alopecia areata.
research Operative Treatment for Androgenetic Alopecia
research Safety and efficacy of tavaborole (AN2690), a novel boron-based molecule, in 3 phase II trials for the topical treatment of toenail onychomycosis
Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.
research Phase separation: a new window in RALF signaling
LLPS is crucial for RALF signaling, aiding plant growth and stress resilience.
research Phytochemical analysis and antibacterial activities of Avicennia marina (Forssk.) Vierh. extracts against Vancomycin-resistant Enterococcus faecium
Avicennia marina leaf extract can fight Vancomycin-resistant bacteria.
research Male and Female Androgenetic Alopecia
AGA causes permanent hair loss; minoxidil helps men, finasteride helps men, minoxidil somewhat helps women, estrogens/antiandrogens lack evidence for women.
research Response to “Reply to effectiveness of dutasteride in a large series of patients with FFA in real clinical practice”
The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.
research AMINOGENIC ALOPECIA LOSS OF HAIR ASSOCIATED WITH ARGININOSUCCINIC ACIDURIA
Argininosuccinic aciduria can cause hair loss.
research PHARMACOTHERAPY ALOPECIA ANDROGENETIC IN MEN
Minoxidil and finasteride are effective long-term treatments for male hair loss.
research Aceclofenac-induced erythema annulare centrifugum
A woman got a skin rash from taking aceclofenac, which went away after she stopped the drug.
research [Finasteride: a new drug for the treatment of male hirsutism and androgenetic alopecia?].
Finasteride may help reduce male hair loss and excessive hair growth by lowering DHT levels.
research Prevalence of androgenic alopecia in women of 20-70 years in Isfahan during 2008-2009
Almost 40% of women aged 20-70 in Isfahan had hair loss, with it being more severe in those with low ferritin levels.
research Etoricoxib
A man had a rare skin reaction from a hair loss medication, which improved after stopping the drug.
research Minimal systemic exposure of a new topical triazole antifungal, efinaconazole 10% solution, in patients with severe onychomycosis following 28-day treatment
Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.
research Use of Topical Minoxidil, 17α-Estradiol and Hydrocortisone Butyrate in Frontal Fibrosing Alopecia
A lotion with minoxidil, hydrocortisone butyrate, and 17a-estradiol can improve or stabilize Frontal Fibrosing Alopecia in some cases, but there's no universally-accepted treatment yet.
research MINOXIDIL FOR MALE-PATTERN BALDNESS
research Effective treatment of refractory alopecia areata in pediatric patients with oral abrocitinib
A new drug, abrocitinib, helped a child with severe hair loss regrow hair.
research Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Transcriptome sequencing and identification of cytochrome P450 monooxygenases involved in the biosynthesis of maslinic acid and corosolic acid in <i>Avicennia marina</i>
Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.