research Pathogenesis of Alopecia Areata in C3H/HeJ Mice and DEBR Rats
Alopecia areata is an autoimmune disease that targets hair follicles.
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research Identification of tpo, tg, tshr and ana antibodies associated with thyroid disorders
Patients with thyroid disorders show different symptoms and antibody levels.
research 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq
The study identified key immune cell differences between mild and severe alopecia areata.
research ISID1373 - Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata
Higher PD-1 levels mean fewer CD8+ T cells in alopecia areata hair follicles.
research Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata
Targeting CXCL10 may help treat alopecia areata.
research scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues
Dual TCR Treg cells are common in mouse tissues and vary by location.
research Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi
Atopy and altered T cell functions contribute to Alopecia Areata.
research The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris
Psoriasis involves an imbalance between certain immune cells, and targeting these could help restore skin health.
research Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level
Diffuse alopecia areata involves more inflammation and higher allergy-related antibodies than patchy types.
research Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata
CD44 variant changes start alopecia areata, but don't maintain it.
research Immunohistochemical localization of TGF‐β in alopecia areata
TGF-β is found in hair follicles and may cause hair loss in alopecia areata.
research - Tumor necrosis factor-alpha inhibitor associated psoriasiform alopecia (drug-induced psoriasiform alopecia)
Some patients on anti-TNF drugs experience a type of hair loss called TAIAPA.
research Associations between type 1 diabetes and autoimmune skin diseases: Mendelian randomization analysis
Type 1 diabetes may cause certain autoimmune diseases in Europeans.
research Alopecia Areata: A Complex Cytokine Driven Disease
Alopecia areata is a hair loss disease caused by complex immune reactions, and new targeted treatments show promise.
research Supplementary Material for: Plasma proteome–driven identification of druggable immune regulators of alopecia areata, validated by transcriptome and single-cell mapping
CD28 is a promising target for treating alopecia areata with belatacept.
research Supplementary Material for: Plasma proteome–driven identification of druggable immune regulators of alopecia areata, validated by transcriptome and single-cell mapping
CD28 is a promising target for treating alopecia areata with belatacept.
research Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature
Developing human skin has immune cells with memory-like features.
research Response to minoxidil in severe alopecia areata correlates with T lymphocyte stimulation
Increased T cell activity may predict hair regrowth success with minoxidil in severe alopecia areata.
research Allergen‐specific immunotherapy improves alopecia totalis in a severe atopic dermatitis patient
Allergen-specific immunotherapy can significantly improve hair loss and dermatitis symptoms in severe cases.
research Иммунологические аспекты гнездной алопеции: от патогенеза к терапевтическим стратегиям
Targeted immune modulation can help achieve stable remission in alopecia areata.
research 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA)
ILC1 cells contribute to hair loss in alopecia areata.
research Skin stem cells orchestrate de novo generation of extrathymic regulatory T cells to establish a temporary protective niche during wound healing
Skin stem cells help create protective immune cells during wound healing.
research 496 Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways
Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.
research Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3
Deleting Snai2 and Snai3 causes fatal autoimmunity.
research Global behavior of solutions in a chemotaxis model for alopecia areata with signal-dependent sensitivity
Sparse hairless patches can develop and stabilize in alopecia areata under certain conditions.
research Local inflammation exacerbates cutaneous manifestations in a murine autoimmune pemphigus model
Local inflammation worsens autoimmune skin conditions by increasing antibody buildup.
research Association between TLR1 polymorphisms and alopecia areata
A specific gene variant (rs4833095) is linked to a higher risk of alopecia areata in Koreans.
research Mendelian Randomization Identifies CD25+ CD4+ Tregs and Plasma Proteins in Androgenetic Alopecia Pathogenesis
Immune cells and plasma proteins are linked to hair loss, suggesting new treatment options.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Chronic urticaria versus dermatomyositis in a case of T- cell large granular lymphocytic leukemia
The muscle damage was caused by T-cell large granular lymphocytic leukemia, not dermatomyositis.