44 citations
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December 2005 in “Journal of Investigative Dermatology” Certain genetic markers, especially the MICA gene, are linked to alopecia areata.
July 2019 in “Dermatology practical & conceptual” The study found that alopecia areata is strongly linked to autoimmune diseases and may indicate a genetic predisposition to such conditions.
18 citations
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January 2013 in “PLoS ONE” HLA-DRB5 and other genes may be linked to alopecia universalis.
25 citations
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May 2017 in “InTech eBooks” Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
10 citations
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April 2003 in “Clinical neurology and neurosurgery” Autoimmune polyglandular syndrome can cause temporary brain issues that may improve on their own.
24 citations
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February 2011 in “The American journal of pathology” AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
71 citations
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October 2013 in “Experimental Dermatology” Vitiligo and alopecia areata may have similar causes despite their differences.
8 citations
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October 2014 in “The Journal of Dermatology” Patients with alopecia areata should be checked for muscle spasms, diarrhea, and ANA to avoid missing Satoyoshi syndrome.
November 2022 in “Journal of Investigative Dermatology” Cell-based therapy using specific immune cells may help treat alopecia areata by promoting hair regrowth.
23 citations
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March 2001 in “Clinics in dermatology” Alopecia areata involves immune response and gene changes affecting hair loss.
September 2024 in “Annals of Dermatology” A new diagnostic model can help better diagnose and understand Alopecia Areata.
1 citations
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January 1989 Four antibodies were developed to help study hair follicle cell differentiation.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
97 citations
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December 2011 in “New England Journal of Medicine” The FDA did not approve certain drugs for prostate cancer prevention due to concerns about their effectiveness and potential risks.
1 citations
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April 2016 in “Journal of Investigative Dermatology” Targeting specific T cells may help treat alopecia areata.
June 2025 in “Frontiers in Immunology” Anti-Ku antibodies are linked to unique symptoms and may involve autophagy issues.
November 2025 in “Journal of Investigative Dermatology” 55 citations
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October 2015 in “Journal of Investigative Dermatology” Alopecia areata is linked to immune-related genes, suggesting JAK inhibitors as a potential treatment.
105 citations
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December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
The nail immune system is similar to hair but different from skin, with fewer immune markers.
8 citations
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February 2015 in “Cellular immunology” Deleting Snai2 and Snai3 causes fatal autoimmunity.
September 2025 in “International Journal of Molecular Sciences” Bacteroides fragilis and Microbacterium sp. T32 may be linked to autoimmune activity in Hashimoto's thyroiditis and alopecia areata.
New treatments for alopecia areata, like JAK inhibitors and immunomodulators, are promising.
12 citations
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March 2023 in “Frontiers in immunology” Atopic dermatitis increases the risk of some autoimmune diseases.
2 citations
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January 2019 The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
50 citations
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May 2021 in “Frontiers in immunology” Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
4 citations
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June 2024 in “Heliyon” Type 1 diabetes may cause certain autoimmune diseases in Europeans.
13 citations
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August 1985 in “The Journal of Dermatology” HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
Alopecia areata patients show increased inflammation and OX40 activation, suggesting a new treatment target.
June 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In alopecia areata, certain immune cells increase and express a protein linked to immune activation.