May 2025 in “International Journal of Molecular Sciences” Exosomes from rat hair follicle stem cells may help heal wounds and regenerate skin.
May 2025 in “Medicine and ecology” The effectiveness of platelet-rich plasma is unclear due to inconsistent preparation methods.
January 2025 in “Dialnet (Universidad de la Rioja)” ADSC-enriched fat grafting is the best and safest aesthetic treatment, combining effectiveness and ethical confidence.
August 2024 in “UPI Journal of Pharmaceutical Medical and Health Sciences” PRP shows promise in musculoskeletal rehabilitation but needs standardized reporting for better outcomes.
January 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Two L-PRP treatments improve hair density in mild to moderate alopecia.
September 2022 in “Applied sciences” Combining micro-needling, LED therapy, and growth factors with Finasteride® significantly improves hair growth.
211 citations
,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
127 citations
,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
118 citations
,
August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
47 citations
,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
30 citations
,
April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
43 citations
,
April 2021 in “Angiogenesis” Lymphatic vessels develop from various cell types and mechanisms, not just veins.
1 citations
,
October 2014 in “Molecular Biology of the Cell” Valentina Greco emphasizes the importance of combining business management with mentoring to run a successful academic lab.
November 2025 in “Frontiers in Pharmacology” Gentamicin-loaded exosomes improve healing of infected diabetic wounds in mice.
April 2024 in “The Journal of experimental medicine/The journal of experimental medicine” Treg cells help repair and regenerate tissues by interacting with local cells.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
4 citations
,
November 2011 in “Archives of Dermatology” Hamilton scale imprecise, hair shaft diameter decreases, stem cell transplant regrows hair, ECP ineffective for alopecia areata universalis.
48 citations
,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
32 citations
,
April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
August 2025 in “Plastic and Aesthetic Research” Microneedling can effectively treat hair loss and works well with other treatments, but more research is needed.
479 citations
,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
320 citations
,
December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
23 citations
,
June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
21 citations
,
October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
15 citations
,
May 2022 in “Journal of Investigative Dermatology” Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
9 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
8 citations
,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
2 citations
,
July 2023 in “International Journal of Molecular Sciences” BFNB could be a promising treatment for hair growth.