research 1250 Development of an ex vivo human skin explant model to examine candidate gene functions in the hair follicle and epidermis
The model can effectively test gene functions and drug responses in human skin.
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research 7 Microneedling and Platelet-Rich Plasma
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
research 475 Paraoxonase 1 (PON1) L55M and Q192R polymorphisms, lipid profiles and psoriasis
The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.
research 477 Dietary fat- and obesity-sensitive dermal adipocyte PKCβ induction and inflammation cross-talk
Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
research 478 Mutation-specific siRNA Knockdown of GJB2 − Potential gene therapy for Keratitis-ichthyosis-deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research 474 Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research Skin Regeneration
New materials and methods could improve skin healing and reduce scarring.
research PRP for skin rejuvenation
PRP is a safe natural treatment that improves skin by reducing wrinkles and enhancing texture for up to 4 months.
research Association between epidermal growth factor and epidermal growth factor receptor gene polymorphisms and susceptibility to alopecia areata in Korean population
Certain gene variations might increase the risk of a hair loss condition in Koreans.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
research Prevention of Temporal Alopecia Following Rhytidectomy
Minoxidil is effective in preventing hair loss after facelift surgery.
research Defining The Role of Primary Cilia on Skin Derived Precursors.
Elongating cilia boosts SKP stem cell renewal, especially with PDGF.
research Evidence from a humanized mouse model of androgenetic alopecia that platelet‐rich plasma stimulates hair regrowth, hair shaft diameter and vellus‐to‐terminal hair reconversion in vivo
PRP helps hair regrowth and thickness.
research Androgenetic Alopecia
PRP and LLLT can improve hair growth in AGA, but more research needed.
research 479 Transcriptomics identifies potential novel therapeutic targets in androgenetic alopecia
Found new possible treatments for hair loss.
research Platelet Rich Plasma in Androgenetic Alopecia- A Prospective Study
Platelet Rich Plasma (PRP) treatment effectively reduces hair fall and increases hair growth in patients with Androgenetic Alopecia (AGA), but it may cause pain.
research Injectable Platelet-, Leukocyte-, and Fibrin-Rich Plasma (iL-PRF) in the Management of Androgenetic Alopecia
iL-PRF treatment improves hair growth for androgenetic alopecia.
research Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting specific immune cells.
research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
research RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells
A new method using human lung cells helps find drugs to block and reduce inflammation from SARS-CoV-2.
research Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapies
Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
research Cutaneous wound healing: canine allogeneic ASC therapy
Using stem cells from fat tissue can significantly improve wound healing in dogs.
research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration
Pro-IGF-II improves muscle repair in old mice.
research Surgical Treatment of Vitiligo
Surgery can help treat vitiligo when other treatments don't work.
research The in vitro plasticity of hair follicle dermal and mesenchymal stem cells
Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
research Guidelines for the management of androgenetic alopecia (2010)
Use minoxidil for hair loss treatment, and finasteride for men.
research Hair Restoration Surgery: The State of the Art
Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.
research Problems and Solutions for Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Review
PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
research Innovations in Skin and Soft Tissue Aging—A Systematic Literature Review and Market Analysis of Therapeutics and Associated Outcomes
Stem cell therapies show the most promise for anti-aging benefits.