A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
January 2018 in “Journal of Investigative Dermatology” Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.
October 2014 in “Cancer research” Blocking mTORC1 reduces skin tumor growth in mice.
July 2010 in “British Journal of Dermatology” New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.
April 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” Polygonum multiflorum may treat hair loss by reducing inflammation and stress, and boosting melanin.
5 citations
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January 2016 in “Genetics and Molecular Research” Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.
August 2023 in “Medical Hypotheses” Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
DHEA inhibits growth in both mouse and human melanoma cells but works differently in each.
177 citations
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March 2018 in “International Journal of Molecular Sciences” mTOR inhibitors may help treat lung fibrosis.
21 citations
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November 2021 in “Cells” Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
20 citations
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November 2022 in “Nutrients” Placenta extract may protect and improve liver health by reducing stress, inflammation, and cell death, and promoting regeneration.
14 citations
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August 2021 in “Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy” Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
June 2025 in “International Journal of Nutrology” A plant-based diet reduces skin inflammation, intermittent fasting supports muscle regeneration, and certain nutrients and supplements aid in healing.
August 2010 in “Journal of Investigative Dermatology” New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.
April 2015 in “Plastic and Reconstructive Surgery” TLR3 activation helps improve skin and hair follicle healing in mice.
14 citations
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May 2017 in “Cell metabolism” Paneth cells and intestinal stem cells work together metabolically for stem cell function and regeneration.
11 citations
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August 2024 in “Nature Communications” Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.
73 citations
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April 2017 in “Scientific Reports” Nitrogen starvation in microalgae increases lipid production, making it a potential biofuel source.
18 citations
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July 2024 in “Frontiers in Immunology” Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
33 citations
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September 2020 in “Current Rheumatology Reports” Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.
2 citations
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June 2024 in “Frontiers in Immunology” 3D cultures can create active macrophages from fat tissue.
33 citations
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March 2018 in “Trends in cell biology” Metabolism plays a key role in determining stem cell fate.
9 citations
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December 2021 in “Journal of Cellular and Molecular Medicine” HAT-MSCs can effectively engulf harmful microbes and particles, aiding infection treatment.
2 citations
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
20 citations
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January 2021 in “GeroScience” Spermidine helps protect against aging by preserving telomere length.
11 citations
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April 2015 in “EBioMedicine” JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.
1 citations
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August 2016 in “Dermatology - Open Journal” Mitochondria change shape to meet energy needs during cell movement.
12 citations
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October 2020 in “Scientific Reports” Necrostatin-1s can promote hair growth and may help treat hair loss.
9 citations
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February 1981 in “Australian journal of biological sciences” Lambs fed a liquid diet showed abnormal wool and skin, which improved with more B-vitamins, suggesting a link to B-vitamin deficiency.
8 citations
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September 2024 in “BMC Genomics” circCFAP20DC helps goat ovarian cells grow, aiding follicle development.