Human Adipose Tissue-Derived Mesenchymal Stromal Cells And Their Phagocytic Capacity

The study investigated the phagocytic capacity of human adipose tissue-derived mesenchymal stromal cells (HAT-MSCs) and found that 33.8% to 56.2% of these cells demonstrated significant phagocytic activity. Using flow cytometry and transmission electron microscopy, the research confirmed that HAT-MSCs could ingest and digest both non-biological materials, like latex beads, and biological targets, such as microorganisms. These findings suggested that HAT-MSCs have an immunomodulatory role and potential clinical relevance in regenerative medicine and immunotherapy, particularly in treating infections and inflammatory processes. Further research was recommended to explore their therapeutic potential.