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research Interaction of the vacuolar H+-pyrophosphatase AVP1 with the secondary transporters AtNHX1 and SOS1 in Arabidopsis thaliana: Implications in salt tolerance and mineral nutrition

January 2006 in “OpenCommons at University of Connecticut (University of Connecticut)”

Overexpressing AVP1 and AtNHX1 in plants improves salt tolerance and root hair development.

research Unraveling Evolutionary Insights into AVT Peptide Conservation and Antimicrobial Motif Prediction Across Taxa

August 2025 in “International Journal of Molecular Sciences”

AVT is highly conserved and may have antimicrobial properties.

research DEFINING THE ROLE OF ABI1 GENE IN PROSTATE CANCER PROGRESSION AND TREATMENT RESISTANCE

January 2024 in “Wiadomości Lekarskie”

The ABI1 gene contributes to prostate cancer progression and treatment resistance.

Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity

research α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity

7 citations , March 2020 in “PloS one”

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality

46 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

research 52243 AH-001: An Emerging Androgen Receptor Degrader Showing Therapeutic Potential in Addressing Androgenetic Alopecia (AGA)

September 2024 in “Journal of the American Academy of Dermatology”

AH-001 could be a safer and more effective treatment for hair loss.

research Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection

7 citations , March 2022 in “Scientific reports”

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

research Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity

11 citations , June 2017 in “Journal of cell science”

AGD1's PH domain is essential for its role in root hair growth and polarity.

research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System

16 citations , April 2000 in “Journal of Investigative Dermatology”

The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.

research NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders

45 citations , July 2025 in “Journal of Medicinal Chemistry”

The document discusses the submission of a New Drug Application (NDA) to the U.S. FDA for vepdegestrant (ARV-471), a PROTAC protein degrader targeting the estrogen receptor, by Arvinas and Pfizer. This submission is based on positive results from the Phase 3 VERITAC-2 trial and marks a significant milestone as vepdegestrant is anticipated to be the first FDA-approved PROTAC degrader. PROTACs, a novel class of molecules, selectively degrade disease-causing proteins and offer advantages over traditional small molecule inhibitors, such as mitigating off-target effects and overcoming drug resistance. Despite concerns about their large molecular weight and drug-like properties, recent clinical results have been promising. The success of PROTACs has inspired the development of other chimeric molecules for therapeutic applications.

research Down-regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in XenopusMelanophores

43 citations , May 1999 in “Journal of Biological Chemistry”

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

research Data Sheet 1_Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling.pdf

September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Angiopoietin-1 helps hair follicle cells survive and grow, potentially treating hair loss.

Functional Analysis of Vitamin D Receptor Using Adenovirus Vector

research Functional analysis of vitamin D receptor (VDR) using adenovirus vector

4 citations , February 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.

Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

research EFFECTS OF α-MELANOCYTE-STIMULATING HORMONE AND [8-ARGININE]-VASOTOCIN UPON MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO

12 citations , December 1981 in “Journal of Endocrinology”

α-MSH increases melanin production in moulting hair follicles, while AVT inhibits it.

research 412 High amphiregulin expression is a high-risk feature of acute graft-versus-host disease of the skin

April 2018 in “Journal of Investigative Dermatology”

High amphiregulin in the skin is a bad sign for acute graft-versus-host disease.

AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity

research AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity

56 citations , December 2011 in “The Plant Journal”

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

70 citations , August 2006 in “Cancer Research”

AP-1 controls tumor cell type by affecting key signaling pathways.

research Novel and recurrent mutations in the AIRE gene of autoimmune polyendocrinopathy syndrome type 1 (APS1) patients

26 citations , September 2009 in “Clinical genetics”

Arab APS1 patients have unique and recurrent AIRE gene mutations.

research BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens

12 citations , June 2025 in “Gut Microbes”

BroadAMP-GPT effectively creates antimicrobial peptides to fight drug-resistant bacteria.

research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation

19 citations , September 2013 in “Psychoneuroendocrinology”

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

research Arabidopsis VILLIN4 is involved in root hair growth through regulating actin organization in a Ca²⁺‐dependent manner

82 citations , January 2011 in “New Phytologist”

VILLIN4 helps root hair growth by organizing actin with calcium.

research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation

12 citations , June 2019 in “Psychoneuroendocrinology”

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

research Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling

September 2025 in “Frontiers in Medicine”

Angiopoietin-1 helps hair cells survive and grow, making it a potential treatment for hair loss.

research Agouti and Agouti-related Protein: Analogies and Contrasts

135 citations , March 2000 in “Journal of Biological Chemistry”

Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.

research A pair of transmembrane receptors essential for the retention and pigmentation of hair

11 citations , May 2012 in “Genesis”

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

Mechanistic Synergy of Hair Growth Promotion by the Avicennia Marina Extract and Its Active Constituent Avicequinone C in Dermal Papilla Cells Isolated From Androgenic Alopecia Patients

research Mechanistic synergy of hair growth promotion by the Avicennia marina extract and its active constituent (avicequinone C) in dermal papilla cells isolated from androgenic alopecia patients

April 2023 in “PLOS ONE”

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.