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AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

A JAK inhibitor improved both severe hair loss and chronic skin disease in one patient.

AP-1 controls tumor cell type by affecting key signaling pathways.

A comprehensive human skin cell atlas was created to better understand skin biology and disease.

Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.

lncRNA VIM-AS1 helps heal diabetic wounds by boosting energy production and reducing cell aging.

Activating Tgr5 may help treat hair loss and bone loss.

Upadacitinib improved both Crohn's ileitis and alopecia universalis in a patient.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.

Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.

Certain immune cells in atopic dermatitis skin could be targeted for treatment.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

New therapies like JAK inhibitors and stem cells show promise in treating vitiligo.

Type IV collagen chains vary in different parts of human skin, with specific patterns linked to melanocytes.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.

Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.

CCCA may involve the PD1/PDL1 pathway and increased caspase 3, leading to permanent hair loss.

Actin and alpha-smooth muscle actin help skin heal in mouse fetuses.

DcR3 helps heal wounds and regrow hair by changing macrophages to a repair-focused type.

A3 antibody helps identify key cells in rat hair follicle development.

Vitamin D receptor and mediator 1 are crucial for healthy skin and hair growth.

Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.

Astrotactin-2 is cleaved in a specific way that helps understand its maturation.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.