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January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
31 citations
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May 2015 in “Stem Cell Reports” Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
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October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
555 citations
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July 2006 in “Journal of biological chemistry/The Journal of biological chemistry” The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
January 2007 in “The Year book of surgery” Mast cells and VEGF contribute to post-surgery adhesions, and blocking VEGF can reduce these adhesions; also, certain factors affect wound healing and fetal skin heals differently with age.
March 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Minoxidil treatment improves heart defects in a DiGeorge syndrome model.
104 citations
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July 1994 in “The Journal of Cell Biology” Basonuclin helps keratinocytes multiply and prevents them from fully maturing.
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March 2013 in “Journal of Applied Biomedicine” β-catenin helps hair follicle stem cells grow by activating a specific cell pathway.
Fgf20 helps form hair follicle structures by stopping cell division and increasing cell movement.
September 2022 in “Institutional Repositories DataBase (IRDB)” The study investigated the differentiation of adipose-derived stem cells (ASCs) into dermal papilla cell (DPC)-like cells using extracellular vesicles (EVs) from DPCs activated with osteogenic and adipogenic inducers. The research demonstrated that the CAO1/2 medium, when supplemented with FGF2 and PDGF-AA, enhanced the expression of hair-inductive genes and maintained DPC-specific properties, leading to increased hair-forming activity. The study highlighted the role of specific microRNAs in regulating hair growth and suggested that DPC-EVs could effectively transform ASCs into cells with hair formation activity. This approach showed potential for hair regeneration therapies, offering a novel method for treating hair-related conditions like alopecia. However, the study acknowledged limitations in understanding miRNA expression and the characterization of DPC-EVs, indicating a need for further research.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sweat gland development involves two unique skin cell programs and a temporary skin environment.
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February 2014 in “Journal of Cutaneous Pathology” Matrical tumors share a common growth mechanism involving the Wnt pathway and consistent PHLDA1 expression.
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July 2017 in “Biochemical and Biophysical Research Communications” The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.
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May 2022 in “International journal of molecular sciences” Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
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February 2023 in “Frontiers in Veterinary Science” Ovine dermal papilla cells are promising for hair growth research due to their stable properties and hair-inducing abilities.
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February 2012 in “Developmental biology” Sostdc1 controls the size and number of hair and mammary gland structures.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Axolotls regenerate their spinal cord through a signal that recruits cells, influenced by cell sensitivity and signal spread.
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April 2009 in “Journal of Investigative Dermatology” The Celsr1 gene is crucial for normal hair patterning in mice.
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March 2015 in “Carcinogenesis” WNT10A helps esophageal cancer cells spread and keep renewing themselves.
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July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.