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New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Bedaquiline, Telmisartan, Diosmin, Azelastine, and Adapalene may be effective treatments for onchocerciasis.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Adapalene, Diosmin, and Azelastine could be repurposed to treat onchocerciasis.

Some dibenzo compounds might help treat cancer with fewer side effects.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Adapalene, Diosmin, and Azelastine may effectively treat onchocerciasis.

Adapalene, Diosmin, and Azelastine may effectively treat onchocerciasis.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Modifying steroidal inhibitors shows promise for developing new cancer treatments.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Created method to measure doxazosin mesylate and finasteride together.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Monocyclic aromatic compounds are important for developing various drugs and treatments.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Epristeride's metabolism in zebrafish helps improve doping detection methods.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

4-azasteroids, including finasteride, can inhibit 5α-reductase, helping treat conditions like enlarged prostate and hair loss.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.

The compound 4c showed strong potential as an anticancer agent.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.