166 citations
,
November 2008 in “Expert Review of Endocrinology & Metabolism” Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
March 1993 in “Neuroscience letters” Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
3 citations
,
May 1990 in “Journal of Steroid Biochemistry” Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.
January 2024 in “Journal of developmental biology” Abdominal skin heals faster than dorsal skin because it has more stem cells.
Supplements improve health, appearance, and athletic performance.
1 citations
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February 2022 in “Journal of the American Academy of Dermatology” Taking biotin supplements can be risky and often lacks evidence of effectiveness for skin, hair, and nail issues.
November 2024 in “PubMed” The supplement improved hair density and was safe to use.
3 citations
,
January 2021 in “Molecular genetics & genomic medicine” The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
February 1994 in “Neuroscience letters” People need different amounts of biotin based on age and it's important for health, with many foods providing enough.
57 citations
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February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
26 citations
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June 2001 in “PTR. Phytotherapy research/Phytotherapy research” Procyanidin B-2 lotion might help men grow thicker hair without side effects.
September 1989 in “Neuroscience letters” People need different amounts of biotin based on age, and not getting enough can cause health problems.
2 citations
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January 2019 in “Elsevier eBooks” Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
July 2025 in “Cosmoderma” The plant-based supplement improved hair, skin, and nail health and boosted well-being without side effects.
10 citations
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April 2020 in “Clinics in Dermatology” Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
1 citations
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June 2019 in “Current developments in nutrition” A combination of arginine silicate complex and magnesium biotinate improves hair and nail growth in rats.
June 2024 in “British Journal of Dermatology” Vitamin B supplements may reverse grey hair.
June 2012 in “한국생활과학회지 = Korean journal of human ecology” The supplement reduced hair loss and increased hair thickness without side effects.
8 citations
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January 2007 in “Hair transplant forum international” Vitamin B12 improves the health and growth of hair micrografts.
2 citations
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July 2023 in “International Journal of Molecular Sciences” BFNB could be a promising treatment for hair growth.
1 citations
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February 2022 in “Biological Trace Element Research” The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
October 2025 in “Phytomedicine” Bazi Bushen capsules reduce skin aging and damage from UV rays.
15 citations
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April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” A3B5 can reduce skin pigmentation and slow melanoma growth.
The conclusion is that hair supplement ingredients may be unsafe and should be disclosed and proven safe before use.
May 2026 in “Journal of Cosmetic Dermatology” The supplement improved hair growth and reduced hair loss effectively.
5 citations
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December 1942 in “Journal of the American Medical Association” Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.
November 2024 in “International Journal of Research in Dermatology” SesZen-BioTM improves skin health and reduces signs of aging.
January 2025 in “Journal of the Korean Society of Food Science and Nutrition” Combining finasteride and black soybean extract better protects hair cells from damage and may treat hair loss effectively with fewer side effects.
89 citations
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January 2020 in “PubMed” Early detection and biotin treatment improve outcomes for biotinidase deficiency.