363 citations
,
May 2006 in “Current Opinion in Psychiatry” Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.
276 citations
,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
262 citations
,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
166 citations
,
February 2005 in “Behavioural brain research” Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.
148 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
147 citations
,
January 2003 in “American journal of clinical dermatology” The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
139 citations
,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
128 citations
,
January 2001 in “American Journal of Clinical Dermatology” Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.
104 citations
,
August 2008 in “Clinics in Dermatology” Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.
100 citations
,
July 2018 in “Journal of The American Academy of Dermatology” People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.
100 citations
,
August 2011 in “Journal of Investigative Dermatology” Lack of vitamin D receptor increases skin tumor risk by boosting hedgehog signaling.
97 citations
,
April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
91 citations
,
April 2017 in “Diabetes & Metabolic Syndrome: Clinical Research and Reviews” Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.
83 citations
,
April 1992 in “Clinical Endocrinology” Having enough iron improves the effectiveness of a specific hair loss treatment in women.
78 citations
,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
78 citations
,
April 1994 in “Archives of dermatology” The study found that Keratosis Pilaris Atrophicans is a genetic skin condition that starts in childhood, involves inflammation and scarring, and current treatments are only somewhat effective.
71 citations
,
August 2019 in “The journal of sexual medicine” Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
68 citations
,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
66 citations
,
June 2018 in “British Journal of Dermatology” European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
62 citations
,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
61 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Beta-catenin is crucial for skin cell growth, development, and cancer formation.
60 citations
,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
53 citations
,
May 2010 in “Journal of Cellular Physiology” Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
51 citations
,
January 2012 in “Annals of dermatology/Annals of Dermatology” A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
42 citations
,
January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
41 citations
,
June 2016 in “Reviews in endocrine and metabolic disorders” Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.
35 citations
,
February 2023 in “Biomolecules” Granzyme B is important in autoimmune skin diseases and could be a new treatment target.
34 citations
,
July 2009 in “Journal of Cell Science” ΔNp63α helps control a protein that stops cancer cells from spreading.
32 citations
,
January 2007 in “Biological & Pharmaceutical Bulletin” Minoxidil and retinol together help hair grow.
31 citations
,
July 2023 in “Nutrients” Vitamin D may help reduce thyroid antibodies and improve thyroid function in Hashimoto's Thyroiditis.