research Androgen receptor gene polymorphisms and risk for androgenetic alopecia: a meta-analysis
G allele of AR Stul polymorphism linked to higher hair loss risk, especially in white people.
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research Tobacco and the skin
Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
research Male androgenetic alopecia: Population-based study in 1,005 subjects
58% of men aged 30-50 have hair loss, with severity increasing with age.
research Hair diameter diversity: a clinical sign reflecting the follicle miniaturization.
Different thicknesses of hair strands can indicate the severity of hair thinning.
research 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene
Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
research MINOXIDIL: HOPE FOR THE BALD?
Minoxidil helps some bald men, but most lose hair again when stopping.
research Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: A cross-sectional study
Higher BMI links to worse hair loss in Taiwanese men.
research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia (Male Pattern Hair Loss)
Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
research Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.
research Androgenetic alopecia: Quality-of-life and associated lifestyle patterns
Hair loss affects quality of life, self-esteem, and confidence, but younger patients cope better.
research New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice
Topical treatments can regrow hair on bald scalps.
research 5‐alpha‐reductase inhibitors are associated with reduced frequency of COVID‐19 symptoms in males with androgenetic alopecia
5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.
research Evaluation of the predictive capacity of DNA variants associated with straight hair in Europeans
Certain DNA variants can predict straight hair in Europeans but are not highly specific.
research Immunohistochemical Evaluation of Androgen Receptor and Nerve Structure Density in Human Prepuce from Patients with Persistent Sexual Side Effects after Finasteride Use for Androgenetic Alopecia
Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
research Promising therapies for treating and/or preventing androgenic alopecia.
There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.
research A hair growth questionnaire for use in the evaluation of therapeutic effects in men
The questionnaire effectively measures men's perceived hair growth and can distinguish between different treatments and dosages.
research Exogen hair characterization in human scalp
The conclusion is that exogen is a unique hair cycle phase and the new sampling method specifically targets this stage, which may help in future hair loss research.
research Androgenetic alopecia in adolescents: A report of 43 cases
Teen hair loss common in boys, linked to family history and mild symptoms.
research Male-Pattern Hair Loss in Norwegian Men: A Community-Based Study
Hair loss common in Norwegian men, affecting self-esteem and life quality.
research Androgenetic alopecia and risk of prostate cancer: A systematic review and meta-analysis
Vertex pattern hair loss linked to higher prostate cancer risk.
research Inhibitory activities of Puerariae Flos against testosterone 5α-reductase and its hair growth promotion activities
Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
research Dermoscopy of scalp tumours: a multi‐centre study conducted by the international dermoscopy society
The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.
research Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp
Minoxidil boosts enzymes that help hair growth.
research Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque.
Finasteride and minoxidil together promote hair growth better than either alone.
research Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy)
Low-level laser therapy effectively treats female hair loss, increasing hair count by 51%.
research Stem cells and alopecia: a review of pathogenesis
Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.