November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.
98 citations
,
December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
39 citations
,
August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
15 citations
,
February 2020 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is crucial for healthy skin barrier function.
January 2026 in “Frontiers in Pharmacology” Cedrol may help treat inflammatory bowel disease by improving gut health and function.
November 2023 in “Elsevier eBooks” Vitamin D affects many body functions and its interaction with microRNAs could help treat related diseases.
147 citations
,
October 2004 in “Experimental dermatology” Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” Diabetic patients' stem cells make vascular grafts more prone to clots, but new methods may improve grafts.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
39 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Fatp4 is crucial for healthy skin development and function.
34 citations
,
August 2019 in “Journal of Allergy and Clinical Immunology” mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
3 citations
,
September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
2 citations
,
September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.
July 2024 in “Journal of Investigative Dermatology” The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
4 citations
,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
April 2026 in “Preprints.org” Bioavailable quercetin may help improve aging signs by positively affecting gut health.
October 2022 in “Chinese Journal of Dermatology” Dry skin does not mean the skin's protective barrier is broken; it's often due to a lack of natural skin moisturizers.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
21 citations
,
December 2015 in “European journal of cell biology” Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
14 citations
,
March 2025 in “Nano Today” The hydrogel dressing speeds up and improves diabetic wound healing.
45 citations
,
November 2024 in “International Journal of Molecular Sciences” Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
1 citations
,
July 2023 in “Nature communications” MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
October 2025 in “Frontiers in Immunology” Platelet-rich plasma might help treat eczema by reducing inflammation and repairing the skin.
April 2018 in “Journal of Investigative Dermatology” Dsg1 is essential for maintaining a healthy skin barrier in mice.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
35 citations
,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
22 citations
,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
17 citations
,
October 2023 in “Molecules” Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.
8 citations
,
July 2022 in “Biomedicines” Autophagy helps keep skin healthy and may improve treatments for skin diseases.
5 citations
,
February 2025 in “Frontiers in Immunology” Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.