research Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis
PPARs help regulate skin health and could be used to treat skin disorders.
Search
for
Sort by
Research
450-480 / 1000+ resultsresearch Embryonic keratinization in vertebrates in relation to land colonization
Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
research Disorders of Keratinization
Understanding genetic mutations helps diagnose and treat skin disorders like ichthyosis.
research Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles
Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
research Age-Related Changes in Male Skin: Quantitative Evaluation of One Hundred and Fifty Male Subjects
Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.
research Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice
Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
research Drug Delivery with Topically Applied Nanoparticles: Science Fiction or Reality?
Nanoparticles show promise for drug delivery through hair follicles but not through healthy skin.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors
Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
research Adult skin acute stress responses to short‐term environmental and internal aggression from exposome factors
Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
research The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling
Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
research Plasticity of Epithelial Cells during Skin Wound Healing
Epithelial cells adapt and work together to heal skin wounds effectively.
research Integral Lipid in Human Hair Follicle
The lipid in human hair follicles acts as a barrier, similar to the skin's lipid layer.
research Fatty acids and related lipid mediators in the regulation of cutaneous inflammation
Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
research Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Practical issues for emollient therapy in dry and itchy skin
Nurses should know about different moisturizers to help patients with dry, itchy skin choose the best one.
research Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles
Nanoplastics can penetrate skin cells, triggering inflammation and immune responses.
research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin
sPLA2-IIE is crucial for normal hair follicle structure and skin health.
research Cutaneous Drug Delivery: An Update
New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
research Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice
Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles
Hair follicles help magnesium get through the skin more effectively.
research ADSCs inhibit photoaging‐ and photocarcinogenesis‐related inflammatory responses and extracellular matrix degradation
ADSCs help protect skin from UV damage and aging.
research Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Can dermal delivery of therapeutics be improved using thermoresponsive nanogels?
Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
research Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 -Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation
The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema
Both emollients effectively reduced itching and improved skin moisture in xerotic eczema.