January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
4 citations
,
January 2015 in “Endocrinology & metabolic syndrome” Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.
98 citations
,
December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
195 citations
,
November 2001 in “The Journal of Cell Biology” Desmocollin 1 is essential for strong skin and proper skin function.
1 citations
,
March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
328 citations
,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
172 citations
,
May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
150 citations
,
June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
130 citations
,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
87 citations
,
January 2017 in “PLoS Genetics” Removing both KLK5 and KLK7 proteins can prevent death and skin issues in Netherton syndrome.
87 citations
,
March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
64 citations
,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
63 citations
,
March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
60 citations
,
July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
50 citations
,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
45 citations
,
January 2020 in “Pharmaceutical Biology” Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
41 citations
,
September 2017 in “Advanced Healthcare Materials” A special hydrogel helps heal skin without scars and regrows hair.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
39 citations
,
January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
38 citations
,
February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
38 citations
,
February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
35 citations
,
December 2017 in “Journal of Experimental Botany” AtCSLD3 and GhCSLD3 genes enhance root growth and cell elongation in plants.
27 citations
,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
24 citations
,
August 2017 in “Prostaglandins & Other Lipid Mediators” CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
23 citations
,
March 2017 in “Journal of Investigative Dermatology” An artificial lipid barrier can restore hair growth in cases of SCD1 deficiency.
23 citations
,
January 2010 in “Journal of Medical Primatology” Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.
22 citations
,
November 2023 in “Molecules” Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
22 citations
,
January 2018 in “Experimental Dermatology” The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
20 citations
,
June 2016 in “Magnesium research” Hair follicles help magnesium get through the skin more effectively.