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LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

A 70-year-old man with skin cancer on both sides of his forehead was treated with surgery and cryotherapy, highlighting the need for early detection and prevention.

HPV8 causes skin cancer by expanding specific skin stem cells.

Older skin has higher cancer risk due to inflammation and stem cell issues.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Cancer-associated fibroblasts promote tumor growth in skin cancer.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

The exact identity of skin stem cells and how skin cells differentiate is not fully known.

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

The number of new cases of cutaneous B-cell lymphoma has leveled off since the early 2000s, and survival rates have improved since 1973.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Targeting vitamin D and androgen receptors may effectively treat triple-negative breast cancer, especially with chemotherapy.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

Dermal-epidermal interactions are crucial for hair growth and maintenance.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Bcl-2 helps hair regeneration but can also increase cancer risk.

Cell proteomic footprinting enhances cancer vaccine quality by ensuring correct antigen composition.

3D bioprinted lung cancer models in a mouse-like structure offer a better way to study radiation effects without using live animals.