17 citations
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June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
14 citations
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December 2016 in “PloS one” Keratin 26 affects cashmere goat hair growth and is influenced by various treatments.
9 citations
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January 2017 in “Annals of Dermatology” The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
6 citations
,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
1 citations
,
February 2013 in “InTech eBooks” Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
May 2025 in “Journal of Developmental Biology” Jawless vertebrates have teeth proteins similar to those in mammalian hair and nails.
July 2023 in “Indian Journal of Animal Health” FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.
August 2019 in “Research Square (Research Square)” Certain long non-coding RNAs in cashmere goats affect hair growth when treated with a specific growth factor.
40 citations
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October 2002 in “Endocrinology” Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
1 citations
,
October 2017 in “ecancermedicalscience” Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
October 2024 in “Archives of Dermatological Research”
134 citations
,
January 2011 in “Development” Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
78 citations
,
May 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes woolly hair and hair loss.
45 citations
,
May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
5 citations
,
February 2019 in “PloS one” Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
610 citations
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April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
555 citations
,
July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
419 citations
,
March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
272 citations
,
September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
253 citations
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
218 citations
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January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
209 citations
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September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
199 citations
,
January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
175 citations
,
April 1982 in “Journal of The American Academy of Dermatology” Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
165 citations
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September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
165 citations
,
January 2008 in “Journal of biomaterials science. Polymer ed.” The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.