49 citations
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May 2021 in “Bulletin of the National Research Centre/Bulletin of the National Research Center” Plantain has potential medicinal benefits but needs more research for safety and effectiveness.
1 citations
,
October 2025 in “Journal of Microbiology and Biotechnology” Natural extracts may promote hair growth with fewer side effects than conventional treatments.
1 citations
,
June 2023 in “Journal of Cosmetic Dermatology” Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.
January 2025 in “BMC Genomics” Key genes and RNA networks regulate hair growth and follicle density in Rex rabbits.
December 2023 in “European Journal of Pharmacology” C3G and Vitisin A may help prevent hair loss by blocking male hormones and stopping hair cell death.
13 citations
,
January 2010 in “Immunopharmacology and immunotoxicology” Diphencyprone increases Bcl-2 protein in patients with hair regrowth from alopecia areata.
10 citations
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August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
Bcl-2 helps hair regeneration but can also increase cancer risk.
January 2014 in “프로그램북(구 초록집)” Platelet-rich plasma treatments help hair growth in people with hair loss by increasing certain cell growth and protein levels.
54 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” 2 citations
,
October 2024 in “Artificial Cells Nanomedicine and Biotechnology” The study investigated the use of Lens culinaris L. total extract (LCTE) for synthesizing silver nanoparticles (LC-AgNPs) and evaluated their anticancer and antimicrobial properties. The LC-AgNPs, characterized as spherical with an average size of 19.22 nm, demonstrated potent cytotoxic activity against MCF-7, HCT-116, and HepG2 cancer cell lines, with IC50 values of 0.37, 0.35, and 0.1 µg/mL, respectively. They induced apoptosis and affected cell cycle phases differently across the cell lines. Additionally, LC-AgNPs showed strong antimicrobial activity against Klebsiella pneumoniae and Acinetobacter baumannii. Molecular docking identified Kaempferol-3-O-robinoside-7-O-rhamnoside and Quercetin-3-D-xyloside as key constituents inhibiting Bcl-2 and IspC cancer targets when combined with the nanoparticles.
138 citations
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April 2003 in “Carcinogenesis” 2-Methoxyestradiol causes cancer cell death by activating specific pathways, but androgens can block this effect.
36 citations
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March 2009 in “Molecular Carcinogenesis” Disrupting Bcl-xL in mice reduces skin cancer risk.
2 citations
,
April 2017 in “Molecular Medicine Reports” Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.
253 citations
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March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
40 citations
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
29 citations
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January 2016 in “Annals of dermatology/Annals of Dermatology” Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.
19 citations
,
June 2002 in “American Journal of Dermatopathology” Apoptosis contributes to hair loss in androgenetic alopecia.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
7 citations
,
March 2005 in “Journal of dermatological science” Apoptosis helps shape hair growth and prepares the skin for hair to emerge.
7 citations
,
September 2019 in “Journal of Cellular Physiology” Akt2 protein is essential for normal cell division in early mouse embryos.
2 citations
,
June 2006 in “Journal of Clinical Pathology” Localized breast cancer can affect skin and hair.
2 citations
,
January 2003 in “PubMed” Hair loss in men might be linked to programmed cell death.
1 citations
,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
1 citations
,
June 2007 in “Journal of Clinical Oncology” Weekly bicalutamide is safe and effective, with 50 mg/week recommended.
April 2025 in “International Journal of Health Sciences” Polyscias scutellaria has potential health benefits, including fighting bacteria, fungi, inflammation, diabetes, cancer, and promoting hair growth.
May 2023 in “Research Square (Research Square)” The HDDPiW-jSB solution may prevent hair loss caused by docetaxel in rats when applied regularly.
October 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking cell death in hair follicles can lead to impaired hair growth.
August 2019 in “Journal of Invertebrate Pathology” Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.
August 2018 in “Journal of Investigative Dermatology” Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.