86 citations
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August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
85 citations
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October 2007 in “International Journal of Dermatology” Curly hair shape is due to uneven growth patterns in the hair follicle.
81 citations
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February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
78 citations
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June 2003 in “Journal of the American Academy of Dermatology” Curly hair shape is determined by the hair bulb.
67 citations
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July 2000 in “Proceedings of the National Academy of Sciences” The model accurately simulates human hair growth and hair loss patterns.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
62 citations
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May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
51 citations
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March 2019 in “Experimental Dermatology” Matrix changes and increased MMPs contribute to skin inflammation in hidradenitis suppurativa.
51 citations
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September 2000 in “Acta dermato-venereologica” PPAR alpha may help in hair growth and could be a target for treatment.
49 citations
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April 2010 in “International Journal of Cosmetic Science” Hair ages as the cuticle wears down, especially beyond 1 meter from the root, affecting its strength and shine.
47 citations
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July 1997 in “British Journal of Dermatology” The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
45 citations
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February 2002 in “International Journal of Cosmetic Science” Ceramide helps protect African–American hair from breakage.
41 citations
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May 2001 in “PubMed” Different thicknesses of hair strands can indicate the severity of hair thinning.
40 citations
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” Changes in keratin make hair follicles stiffer.
39 citations
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November 2007 in “Experimental dermatology” Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.
34 citations
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April 2009 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
33 citations
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March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
29 citations
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April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
28 citations
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January 2016 in “Dermatology” Methotrexate with corticosteroids can effectively treat severe alopecia areata but often requires long-term maintenance.
28 citations
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August 2005 in “Journal of Investigative Dermatology” TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.
26 citations
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July 2006 in “International Journal of Cosmetic Science” Taurine helps protect and promote hair growth.
23 citations
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June 2019 in “Bioanalysis” Monitoring steroid hormones in blood can better detect testosterone doping.
23 citations
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July 1997 in “British Journal of Dermatology” The inner root sheath is vital for hair follicle stability during growth changes.
22 citations
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June 2008 in “Experimental Dermatology” Heparanase is essential for hair follicle health and inner root sheath differentiation.
22 citations
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February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
20 citations
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December 2006 in “Archives of dermatology”
20 citations
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December 1995 in “International Journal of Pharmaceutics” Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
18 citations
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June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
16 citations
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August 2003 in “Journal of The American Academy of Dermatology” Nitrogen mustard was not very effective for hair regrowth in alopecia areata and has potential skin cancer risk.