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Medications Affecting the Insulin-Like Growth Factor 1/Growth Hormone Axis, Including Teprotumumab, Somatostatin Analogs, and Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies, Are Associated With Elevated Reporting Odds of Alopecia in Women: A Pharmacovigilance Study

research Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study

April 2023 in “Journal of The American Academy of Dermatology”

Some drugs linked to growth hormones may increase the chance of hair loss in women.

research Treatment of vitiligo with the topical Janus kinase inhibitor ruxolitinib: A 32-week open-label extension study with optional narrow-band ultraviolet B

74 citations , February 2018 in “Journal of the American Academy of Dermatology”

research Hirsutism following the use of bimatoprost eyedrops for glaucoma

2 citations , July 2014 in “Journal of pharmacology and pharmacotherapeutics”

A woman got unwanted hair growth on her face from using bimatoprost eyedrops for glaucoma.

research Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma

234 citations , September 2004 in “Clinical cancer research”

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

research Effect Of Short Term Administration Of Metformin On Endocrine And Clinical Parameters in Overweight/ Obese Polycystic Ovarian Syndrome (PCOS) Women

December 2023 in “Advances in basic medical sciences.”

Metformin improved menstrual cycles and cholesterol but didn't change weight or hormone levels in the short term for overweight PCOS women.

research Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study

29 citations , April 2019 in “BMJ. British medical journal”

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

research Baricitinib Treatment Increases Eyebrow and Eyelash Regrowth Up to 52 Weeks

November 2023 in “Skin”

research Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms

15 citations , August 2010 in “Fertility and sterility”

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors

64 citations , March 2008 in “Neuropsychopharmacology”

Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?

research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?

6 citations , April 2014 in “European journal of medicinal chemistry”

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

research Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice

5 citations , January 2015 in “Molecular Genetics and Metabolism”

Sinapic Acid and Glabridin Synergistically Mitigate Androgenetic Alopecia by Modulating Ferroptosis Through Stabilization of Beta-Catenin Against Ubiquitin-Dependent Degradation

research Sinapic acid and glabridin synergistically mitigate androgenetic alopecia by modulating ferroptosis through stabilization of β-catenin against ubiquitin-dependent degradation.

July 2025 in “PubMed”

Sinapic acid and glabridin together help hair growth in androgenetic alopecia.

research Efficacy and tolerability of oral bicalutamide in forty postmenopausal women with female pattern hair loss: a retrospective study

December 2025 in “Actas Dermo-Sifiliográficas”

Bicalutamide may improve hair growth in postmenopausal women with mild side effects.

research Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome.

40 citations , April 2008 in “European journal of endocrinology”

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

research Long-term toxicologic and tumorigenesis studies on an oral contraceptive agent in albino rats

61 citations , January 1970 in “Toxicology and Applied Pharmacology”

Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin

research Hair regrowth in 2 patients with recalcitrant central centrifugal cicatricial alopecia after use of topical metformin

24 citations , January 2020 in “JAAD Case Reports”

Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.

research Two novel BTD mutations causing profound biotinidase deficiency in a Chinese patient

3 citations , January 2021 in “Molecular genetics & genomic medicine”

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

research The Dark Side of Gefitinib: Reflectance Confocal Microscopy Applied to Hair Hyperpigmentation

4 citations , October 2019 in “Skin Appendage Disorders”

Gefitinib can cause hair and eyebrow darkening.

All-In-One Polysaccharide Hydrogel With Resistant Vascular Burst Pressure And Cooperative Wound Microenvironment Regulation For Fatal Arterial Hemorrhage And Diabetic Wound Healing

research All-in-one polysaccharide hydrogel with resistant vascular burst pressure and cooperative wound microenvironment regulation for fatal arterial hemorrhage and diabetic wound healing

June 2024 in “International journal of biological macromolecules”

The hydrogel effectively stops bleeding and heals diabetic wounds quickly.

research Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1

12 citations , June 2001 in “Bioorganic & Medicinal Chemistry”

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite

research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite

3 citations , March 2017 in “Regulatory toxicology and pharmacology”

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

research Mechanistic perspectives on the dermatologic potential of topical metformin: A scoping review

August 2025 in “World Academy of Sciences Journal”

Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.

research Effect of Metformin Therapy on Clinical and Hormonal Indices of Patients with Polycystic Ovary Syndrome

May 2021

Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.

research Finasteride with Doxazosin to Reduce BPH Progression

March 2005 in “The Nurse Practitioner”

Supplementary Material for: Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro

research Supplementary Material for: Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro

January 2021 in “Figshare”

Metformin helps regenerate hair follicles in lab conditions.

research Glucose-Activated Nanoreactor Initiating Cascade Reaction to Remodel Immune Microenvironment for Promoting Diabetic Wound Healing

March 2026 in “ACS Applied Materials & Interfaces”

MCP@G improves diabetic wound healing by reducing stress and promoting tissue repair.

research Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique

1 citations , January 2024 in “NPJ breast cancer”

Experts agree on how to manage sugar levels and skin reactions in patients taking the cancer drug alpelisib.

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