14 citations
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February 1998 in “Bioorganic & Medicinal Chemistry Letters” Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
8 citations
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April 2020 in “Journal of The American Academy of Dermatology” Bicalutamide may be a promising alternative treatment for female pattern hair loss.
April 2026 in “The Journal of Steroid Biochemistry and Molecular Biology” Baicalin may effectively treat hair loss by inhibiting 5α-reductase.
Metformin can cause rare severe skin reactions.
May 2019 in “Pakistan Journal of Pharmaceutical Sciences” Metformin can effectively treat PCOS but may cause serious side effects like joint pain and allergic reactions.
11 citations
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December 2017 in “Diabetes Therapy” Recognizing and treating early signs of insulin resistance can help prevent type 2 diabetes and improve life quality.
April 2019 in “Journal of the Endocrine Society” Androgens and estrogens are crucial for insulin secretion in males.
January 2017 in “Journal of Pakistan Association of Dermatologists” April 2019 in “Journal of the Endocrine Society” A woman's severe insulin resistance improved with treatment, but she still had high testosterone levels due to ovarian issues.
17 citations
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December 2015 in “Bioorganic & Medicinal Chemistry” 3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
October 2025 in “EMJ Dermatology” GLP-1RA therapy may increase the risk of hair loss.
48 citations
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February 2025 in “Advanced Materials” The hydrogel speeds up diabetic wound healing by adapting to glucose levels and releasing insulin.
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November 2003 in “Current Opinion in Obstetrics & Gynecology” Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
1 citations
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May 2022 in “Frontiers in Pharmacology” Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
January 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” Topical GT20029 effectively promotes hair regrowth and is well-tolerated.
2 citations
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February 2005 in “Postgraduate obstetrics & gynecology” Certain medications can help treat PCOS symptoms, but they aren't FDA-approved for this use.
4 citations
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November 2021 in “Journal of The American Academy of Dermatology” Bicalutamide may reduce unwanted hair growth caused by minoxidil in women with hair loss.
17 citations
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July 2016 in “The Prostate” Metformin may lower PSA levels, possibly affecting prostate cancer development.
The hydrogel significantly improves healing in diabetic wounds.
July 2024 in “Reactions Weekly”
GLP-1 receptor agonists for weight loss may cause hair loss, especially in women.
9 citations
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August 2024 in “Australian Prescriber” PCOS treatment should be personalized, using birth control pills or metformin for symptoms, with lifestyle changes being essential.
7 citations
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August 1996 in “The Journal of Clinical Endocrinology and Metabolism” October 2016 in “Letters in Drug Design & Discovery”
October 2025 in “JEADV Clinical Practice” GLP-1 receptor agonists may increase the risk of a specific type of hair loss called androgenetic alopecia.
44 citations
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October 2016 in “Epilepsia” 2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
96 citations
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February 2007 in “The Journal of Clinical Endocrinology & Metabolism” Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.
May 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.