202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
1425 citations
,
September 2020 in “Open Biology” Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
September 2019 in “Journal of Investigative Dermatology” Specialized ribosomes affect aging in human skin cells.
July 2024 in “Journal of Investigative Dermatology” Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” Age-related hair loss is linked to changes in blood vessels, stem cells, and aging cells, and understanding these can help keep hair healthy as we age.
April 2023 in “Journal of Investigative Dermatology” Proper cell death regulation is crucial for normal hair follicle regeneration and skin remodeling.
3 citations
,
July 2015 in “European Journal of Dermatology” AGEs may cause hair loss by increasing inflammation in hair follicles.
70 citations
,
July 2016 in “Aging” Targeting dermal adipocytes may help combat skin aging.
252 citations
,
February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
1 citations
,
November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
41 citations
,
July 2018 in “Frontiers in Neurology” Myotonic dystrophy may be classified as a segmental progeroid disorder.
10 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
1 citations
,
April 2015 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” Skin and hair aging involves mitochondrial issues, telomere shortening, and hormonal changes, with iron affecting hair loss in pre-menopausal women.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Restoring cell communication can treat tissue disorders.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Restoring cell communication can treat tissue disorders.
10 citations
,
October 2017 in “Dermatologic clinics” Aging in men is influenced by genetics and lifestyle, leading to muscle loss, bone issues, and skin damage.
70 citations
,
March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
May 2013 in “Springer eBooks” Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
150 citations
,
August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
October 2025 in “PLoS ONE” Age-related hearing loss involves cochlear damage and metabolic changes.
20 citations
,
September 2022 in “Journal of Biomedical Optics” PBM helps improve cell survival in 3D tissue engineering.
September 2024 in “Journal of Inflammation Research” Type 1 Diabetes prevents hair growth by causing cell death in hair follicles.
October 2024 in “Benha Journal of Applied Sciences” Androgenetic alopecia is linked to aging due to inflammation, oxidative stress, and hormonal changes.
December 2024 in “American Journal of Biomedical Science & Research” Stem cell therapy shows promise for regenerating tissues and treating diseases, especially in older people.
Senescence and genomic instability in fibroblasts contribute to hair loss and impaired skin regeneration with age.
46 citations
,
February 1983 in “The Journal of Dermatology” Hair regrowth slows with age due to changes in enzyme activity.
January 2025 in “JCEM Case Reports” Enzyme replacement therapy may help alleviate symptoms in complex cases like this.
520 citations
,
January 2017 in “AIMS biophysics” Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
3 citations
,
December 2021 in “IntechOpen eBooks” Bionanomaterials from natural sources show promise in improving wound healing and tissue regeneration.
59 citations
,
November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.