research The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
3D skin models better mimic human skin and melanoma progression than older methods.
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780-810 / 1000+ resultsresearch Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
research Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)
Human skin can produce steroids from cholesterol.
research Sebaceous gland organoid engineering
Sebaceous gland organoids could improve skin regeneration and treatment.
research Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing
Controlling immune responses with biomaterials can reduce scarring and improve skin regeneration.
research Analysis of skin graft survival using green fluorescent protein transgenic mice
GFP transgenic mice help study cell origins in skin grafts.
research Biodegradable Polysaccharide Gels for Skin Scaffolds
Biodegradable polysaccharide gels can improve skin healing and reduce scarring.
research Vascularization of skin substitute constructed by vascular endothelial growth factor 165 gene-modified hair follicle stem cells compounded with three-dimensional gelatin-chondroitin sulfate-hyaluronic acid
The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.
research MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis
MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
research LB1671 Large-scale skin scRNA-seq profiling highlights distinct body site-specific ligand-receptor interactions and pathways in keratinocytes
Different body areas have unique skin cell communication patterns, explaining why certain skin diseases occur in specific regions.
research Clinical Considerations of Bioequivalence for Topical Dermatologic Drugs
Current methods for assessing bioequivalence of topical drugs are limited and lack standardization.
research [Skin-like structure generated from implantation of hair follicle bulb cells into collagen/chitosan porous scaffolds in vitro].
Hair bulb cells can create skin-like tissues for potential skin repair.
research 1347 Updated skin transcriptomic atlas depicted by reciprocal contribution of single-nucleus RNA sequencing and single-cell RNA sequencing
The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.
research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Recombinant Bacillus subtilis-derived alkaline protease: a novel agent for skin depigmentation and hair follicle neogenesis
research Commentary: Hair Transplantation for Reconstruction of Scalp Defects using Artificial Dermis
Artificial dermis used for hair transplantation can reconstruct scalp defects effectively without the need for tissue expansion.
research A volar skin excisional wound model for in situ evaluation of multiple-appendage regeneration and innervation
The study concluded that the new wound model can be used to evaluate skin regeneration and nerve growth.
research Topical Application of Bio-Pulsed Avian MSC-Derived Extracellular Vesicles Enhances Hair Regrowth and Skin Rejuvenation: Evidence from Clinical Evaluation and miRNA Profiling
Bio-Pulsed sEVs improve hair growth and skin rejuvenation.
research Differences in Human Skin Between the Epidermal Growth Factor Receptor Distribution Detected by EGF Binding and Monoclonal Antibody Recognition
research Skin Graft Harvesting and Donor Site Selection
The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Ultrasound-ActivatedGelMA Hydrogel Loaded with MSC-EVsPromotes Functional Regeneration of Skin Vasculature, Nerves, andAppendages
Ultrasound and GelMA hydrogel with stem cell vesicles improve skin healing and regeneration.
research THE EXPRESSION CHARACTERISTICS AND THEIR BIOLOGICAL SIGNIFICANCE OF EPIDERMAL GROWTH FACTOR AND BASIC FIBROBLAST GROWTH FACTOR IN RAT SKINS AT DIFFERENT DEVELOPMENT STAGES
EGF aids skin development and healing, while bFGF absence in embryos may allow scar-free healing.
research 454 Modeling epidermolysis bullosa simplex with cardiomyopathy using KLHL24-mutant pluripotent stem cells.
KLHL24-mutant stem cells help understand skin and heart disease.
research Hair Follicle-Derived Smooth Muscle Cells and Small Intestinal Submucosa for Engineering Mechanically Robust and Vasoreactive Vascular Media
Hair follicle cells and intestinal tissue can create strong, functional blood vessel replacements.
research Basement Membranes in Experimentally Induced Skin Tumors
research Template for Skin Regeneration
The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
research Hair follicle-derived epithelial sheet has potential in vitiligo treatment
Hair follicle-derived sheets can effectively treat vitiligo by repigmenting skin.
research Skin-permeable liposome improved stability and permeability of bFGF against skin of mice with deep second degree scald to promote hair follicle neogenesis through inhibition of scar formation
A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
research Development of a mechanically stable human hair keratin film for cell culture
A new film made from human hair supports skin cell growth better than collagen.