research Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route
Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
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research BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FINASTERIDE, TADALAFIL, AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN RAT PLASMA BY USING LC-MS/MS
A reliable method was developed to measure Finasteride and Tadalafil in rat blood.
research PC-SPES Studies Promising, But Manufacturer Shuts Down
Promising cancer treatments were found, but the manufacturer closed.
research Quantification of biotin in plasma samples by column switching liquid chromatography – tandem mass spectrometry
The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.
research Contents
Biologicals are increasingly used in medicine and cosmetics, especially for skin and hair treatments, but more research is needed.
research Caractérisation physique et chimique des substances à activité thérapeutique : application aux études de profil de stabilité et de préformulation
APIs' stability is influenced by crystalline forms, pressure, and water.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis
Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
research Development of 3-D Microbioreactor Systems for Cell-Based High Throughput Screening
A new 3-D bioreactor system improves drug screening and reduces animal testing.
research Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol
Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
research Re‐Innovation in Clinical Trial Designs Based on Precision Therapy
Clinical trials should use innovative designs and biomarkers to improve precision therapy and patient outcomes.
research Reporting in clinical studies on platelet-rich plasma therapy among all medical specialties: A systematic review of Level I and II studies
The review concluded that reporting on PRP therapy is often incomplete, leading to uncertainty about its effectiveness.
research Bioequivalence Study of Finasteride Tablets in Human Plasma by HPLC-MS
The test and reference finasteride tablets are bioequivalent.
research The Pharma Market as Reflected by Patents
The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
research High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile
Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
research Bioequivalence Study of Finasteride
Finasteride's two formulations absorb similarly, showing bioequivalence.
research 144 Evaluation of contamination and quantification of drug penetrations studies using Quantitative Mass Spectrometry Imaging
QMSI effectively maps and quantifies drug distribution in skin tissues.
research P-215 Study on Bioequivalence of Finasteride Tablet in Healthy Volunteers
research Data-driven strategies for drug repurposing: insights, recommendations, and case studies
Drug repurposing can speed up and reduce costs in drug discovery, especially for cancer treatment.
research Determination of Exemestane in Human Plasma by LC-MS-MS
The method effectively showed that the two exemestane preparations are bioequivalent.
research Preformulation studies of finasteride to design matrix systems for topical delivery
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research Fronteggiare l’inaffidabilità della letteratura da studi clinici
Public health decisions should rely on independent trials, not biased literature.
research Determination of Finasteride in Human Plasma by HPLC-MS and Study on the Bioequivalence of Domestic and Import Finasteride Tablets
Domestic and imported finasteride tablets are bioequivalent.
research Tracing Recombinant Bovine Somatotropin Ab(Use) Through Gene Expression in Blood, Hair Follicles, and Milk Somatic Cells: A Matrix Comparison
Gene expression in milk cells and blood can help detect illegal rbST use in cows.
research PSS33 REAL-LIFE DOSING OF BIOLOGICS IN PLAQUE PSORIASIS—A GERMAN SURVEY
Real-life dosing of biologics for plaque psoriasis often deviates from recommended guidelines, especially for high-need patients.
research Post-Drug Syndromes: A Neglected Challenge in Pharmacovigilance and Public Health
Current drug safety systems fail to detect long-term side effects, leading to preventable health issues.
research Medical Technologies: Pharmaceutical Cosmetology, Cosmeceuticals – Opportunities and Limitations
Cosmeceuticals effectively treat skin issues but need better regulation and safety measures.
research Data-driven strategies for drug repurposing: insights, recommendations, and case studies
Data-driven methods can effectively identify existing drugs for new uses, especially in cancer, infections, and respiratory diseases.
research Post-Drug Syndromes: A Neglected Challenge in Pharmacovigilance and Public Health
Current drug safety systems fail to detect long-term side effects, needing improvements to protect health and trust.