research Spotlight Commentary: Importance of dose redefining in the process of drug repurposing
Redefining drug dosages is crucial when repurposing them for new uses.
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Generic drugs for benign prostatic hyperplasia can cost up to 500% more at chain pharmacies compared to independent ones.
research Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review
Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Characterization of Plant-Based Biotin from SesZenBioTM and In silico Studies to Prove Its Potential in Hair Care
Plant-based biotin from SesZenBioTM could be twice as effective as synthetic biotin for hair care.
research Randomized controlled trial on a PRP-like cosmetic, biomimetic peptides based, for the treatment of alopecia areata
The PRP-like cosmetic with biomimetic peptides is potentially effective and safe for treating alopecia areata.
research Direct-to-consumer Androgenetic Alopecia treatments: A Cost Comparison with traditional pharmacies
research Recent European legal developments on second medical uses and dosage regimes
European patent law now allows patents for new uses and dosages of known drugs, but protection scope is unclear.
research Wnt is back in drugmakers' sights, but is it druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
research Synthesis and biological screening of small molecule peptides based on the amino acid sequence of thymosin β4
Some synthesized peptides improved cell growth better than thymosin β4, VEGF, and minoxidil.
research UK High Court Revokes Escitalopram UK Patent; Validity of Second Medical use Claims Based on Dosage Regimes in the UK; Stay of Proceedings in the UK Courts Pending EPO Opposition Proceedings
The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
research Determination of illegal adulteration of dietary supplements with synthetic hair-growth compounds by UPLC and LC-Q-TOF/MS
The new method accurately detects illegal hair-growth drugs in dietary supplements.
research Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist
The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.
research Drug–DrugCoamorphous System of Tadalafil andFinasteride for Enhanced Pharmaceutical Performance
A new combination of tadalafil and finasteride improves drug performance and stability.
research Synthesis and biological activity evaluation of new isatin-gallate hybrids as antioxidant and anticancer agents (in vitro) and in silico study as anticancer agents and coronavirus inhibitors
New isatin-gallate hybrids show promise as antioxidants, cancer treatments, and coronavirus inhibitors.
research Sprayable biomimetic double mask with rapid autophasing and hierarchical programming for scarless wound healing
The new sprayable wound mask helps heal wounds without scars.
research Disproportionality analysis comparing safety profiles of sonidegib and vismodegib based on the FAERS database
Sonidegib and vismodegib have different side effects and reporting patterns.
research INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Human serum albumin nanoparticles for enhanced drug delivery to treat breast cancer: Preparation and In Vitro assessment
HSA nanoparticles can improve tamoxifen delivery for breast cancer treatment, reducing side effects.
research Nanoemulgel as an innovative platform for phytomolecules
Nanoemulgel improves delivery and effectiveness of plant-based drugs for various conditions.
research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.
research The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis
BMS-470539 reduces skin fibrosis and inflammation.
research Emulgel: A Novel Strategy for Enhanced the Topical Drug Delivery
Emulgel improves skin delivery of various drugs better than traditional methods.
research 'The Byzantine logic of patent law jurisprudence': patent protection for dosage regimes revisited
UK courts and the European Patent Office are now more open to granting patents for new dosage regimes.
research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors
New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
research Original article / Article original Counterfeit drugs and pharmaceutical preparations seized from the black market among bodybuilders Médicaments de contrefaçon et préparations pharmaceutiques saisis sur le marché noir parmi les bodybuilders
Counterfeit drugs for bodybuilders often contain incorrect or contaminated ingredients and look like real products.
research Follicular delivery of a novel peptide therapeutic for the treatment of androgenic alopecia
A new peptide, murikal/SPR4, was found to significantly increase hair growth in mice, and its liposomal topical formulations enhanced hair growth more than commercial products. However, results on human scalp skin were unclear, needing more tests.
research Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review
These new skin treatments are safer and more effective with minimal side effects.
research Poster abstract: Novel dissolving microarray patches for intradermal delivery of finasteride
Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.
research Synthesis and bioactivity of new Finasteride conjugate
New Finasteride conjugate improves prostate treatment and vital signs in rats.
research Simultaneous spectrophotometric determination of finasteride and tadalafil in recently FDA approved Entadfi™ capsules
The methods accurately measure finasteride and tadalafil in Entadfi™ capsules for quality control.