research Development of 3-D Microbioreactor Systems for Cell-Based High Throughput Screening
A new 3-D bioreactor system improves drug screening and reduces animal testing.
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research Histomorphological Study of Nail Changes in Various Dermatoses — An Understudied Entity in Dermatopathology
Examining nail biopsies is useful for diagnosing nail diseases.
research Editorial Board
People need different amounts of biotin based on age, and not getting enough can cause health problems.
research Clinical, biochemical and mutational findings in biotinidase deficiency among Malaysian population
Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.
research The Follicle Inference Engine (FIE): A stochastic digital twin and optimal experimental design framework for androgenetic alopecia
research Integrated edge information and pathway topology for drug-disease associations
iEdgePathDDA effectively finds new drug-disease links, outperforming other methods.
research Solid-Phase Microextraction and Related Techniques in Bioanalysis
research Drug Repositioning with GraphSAGE and Clustering Constraints Based on Drug and Disease Networks
The method effectively predicts new drug uses, including potential COVID-19 treatments.
research Transcriptional Profiling in Rat Hair Follicles following Simulated Blast Insult: A New Diagnostic Tool for Traumatic Brain Injury
Hair follicles can help diagnose traumatic brain injury quickly and non-invasively.
research Forensic DNA Phenotyping: a review on SNP panels, genotyping techniques, and prediction models
Forensic DNA phenotyping faces challenges due to inconsistent terminology, limited genetic understanding, and debates over technology and models.
research Plucked human hair as a tissue in which to assess pharmacodynamic end points during drug development studies
Plucked human hair can be used to study drug effects on certain cell markers.
research Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Editorial Comment
More biopsy cores and MRI before biopsy can improve prostate cancer detection.
research 224 Humoral immune response to COVID-19 vaccination in psoriasis patients on biologic therapy is impaired compared to healthy controls
Psoriasis patients on biologic therapy have a weaker immune response to COVID-19 vaccination than healthy people.
research Perbandingan Kadar Transforming Growth Factor-Beta 1 pada Platelet Rich Plasma dengan Metode Pure dan Buffy Coat pada Populasi Individu Sehat
The buffy coat method yields higher TGF-β1 levels in PRP, especially in males.
research A Characterization of Disparities in Published Alopecia Quality of Life Studies
research A Hybrid Transfer Learning Approach Using Obesity Data for Predicting Cardiovascular Diseases Incorporating Lifestyle Factors
Adding obesity data to machine learning models improves heart disease prediction accuracy.
research Application of the waiting time distribution in a nationwide screening of real‐world dermatology drug utilization for aberrant use patterns
Most dermatology drugs in Denmark are used correctly, with few unusual patterns.
research DrugNet: Network-based drug–disease prioritization by integrating heterogeneous data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.
research The quantification of reproductive hormones in the hair of captive adult brown bears and their application as indicators of sex and reproductive state
Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.
research ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS
Stat3 affects skin cancer development by altering keratinocyte stem cell behavior.
research The current state of play in the histopathologic assessment of alopecia: two for one or one for two?
The document concludes that choosing the right biopsy site is crucial for accurate alopecia diagnosis, and combining methods can improve results.
research Physiological analysis of Iraqi male patients with hair loss: A cross-sectional study
Men with hair loss may have more body fat and different blood characteristics.
research Optimization of finasteride nano-emulsion preparation by using chemometrics approaches (and/or Box-Behnken design and regresion model)
research Low serum biotin in Japanese children fed with hydrolysate formula
Japanese infants fed hydrolysate formula may have low biotin levels.
research Pervasive structural racism in environmental epidemiology
Environmental health research must address racism to improve health outcomes for BIPOC communities.
research Isolated hair bacteria reveal different isolation possibilities under various conditions
Different conditions affect how easily hair bacteria can be isolated.
research Post-marketing safety profile of cladribine in multiple sclerosis: a disproportionality analysis based on the FDA adverse event reporting system
Cladribine has known risks and potential new safety concerns, requiring careful monitoring.