166 citations
,
November 2008 in “Expert Review of Endocrinology & Metabolism” Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.
50 citations
,
May 1985 in “The journal of pediatrics/The Journal of pediatrics” Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.
43 citations
,
April 2005 in “The Journal of Dermatology” Biotin supplements improved skin and hair in a biotin-deficient infant on amino acid formula.
31 citations
,
February 1983 in “American Journal of Clinical Nutrition” Biotin deficiency can cause hair loss in adults on long-term TPN, but supplementation helps regrow hair.
29 citations
,
July 1996 in “Acta Paediatrica” Biotin should be added to Japanese amino acid formula to prevent deficiency.
26 citations
,
May 1984 in “Journal of Parenteral and Enteral Nutrition” Biotin supplements restored hair and resolved symptoms in a woman with biotin deficiency.
21 citations
,
January 1945 in “Journal of Nutrition” Biotin deficiency in monkeys causes fur and skin issues, but 20 μg of biotin daily can prevent or cure it.
11 citations
,
September 2010 in “PubMed” Zinc and biotin supplements are needed after certain surgeries to prevent hair loss and other issues.
10 citations
,
September 2013 in “Nutrition” The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
2 citations
,
March 2020 in “PubMed” Biotin deficiency is not a major cause of Telogen Effluvium hair loss.
2 citations
,
January 1997 in “Journal of Clinical Biochemistry and Nutrition” Biotin deficiency causes severe hair loss and weight reduction in germ-free mice.
GV-350 improves hair growth and quality of life in iron-deficient women without side effects.
55 citations
,
July 1983 in “Journal of the American Academy of Dermatology” Biotin supplements can effectively treat hair loss and skin issues in certain enzyme deficiencies.
2 citations
,
August 2024 in “Molecular Genetics & Genomic Medicine” Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.
184 citations
,
August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
89 citations
,
January 2020 in “PubMed” Early detection and biotin treatment improve outcomes for biotinidase deficiency.
82 citations
,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
79 citations
,
January 2017 in “Dermatology practical & conceptual” Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.
71 citations
,
January 2016 in “International Journal of Trichology” Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.
57 citations
,
February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
31 citations
,
September 2010 in “Current Opinion in Clinical Nutrition & Metabolic Care” Micronutrient deficiencies may cause hair loss in people on long-term parenteral nutrition.
13 citations
,
August 2020 in “Journal of Laparoendoscopic & Advanced Surgical Techniques” Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.
10 citations
,
April 2020 in “Clinics in Dermatology” Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
6 citations
,
April 2019 in “Nutrients” Biotin is important for keeping zinc levels balanced in the skin and its lack can cause hair loss.
5 citations
,
October 2019 in “Giornale italiano di dermatologia e venereologia” Biotin supplements can improve certain skin disorders and hair loss when a deficiency is present.
4 citations
,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
4 citations
,
January 1986 in “PubMed” Serum biotin levels can indicate biotin deficiency in sows.
2 citations
,
January 2019 in “Elsevier eBooks” Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
2 citations
,
December 2014 Low biotin intake during pregnancy can affect biotin transport in mothers and fetuses.
1 citations
,
December 2017 in “Skin appendage disorders” Biotin may help women with hair loss who have low biotin levels, but more research is needed.