research High-throughput screening of small molecule Wnt/β-catenin activators for hair and nail growth
Certain compounds can boost hair and nail growth.
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research Trajectories For Scalp Hair Regrowth In Patients With Severe Alopecia Areata Treated With Baricitinib
Baricitinib helps patients with severe alopecia areata regrow hair.
research Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin
Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
research Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with D-limonene
Sonophoresis reduces skin absorption of sodium fluorescein in certain liposomes.
research 1435 Enzymatic digestion of scalp hair follicle bulge allows to have more bulge-derived stem keratinocytes than explant isolation
Using enzymes to break down scalp hair follicles gets more stem cells for skin and hair growth than the old method.
research Transdermal Liposomal Delivery Systems: Advantages, Applications, Challenges, and Prospects
Liposomal delivery systems improve drug absorption through the skin, offering potential for better treatments.
research Bioengineering of Hair Follicle-like Structure for Validation of Hair Growth Promoting Compounds
The method can test hair growth products using a lab-made hair-like structure that responds to known treatments.
research PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery
PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
research In vitro Keratin Expression of Hair Cells
Hair cells grown in a lab showed specific hair proteins.
research CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.
research In Vitro Biosynthesis of Mouse Hair Keratins Under the Direction of Follicular RNA
research Peer Review #3 of "Nature-derived lignan compound VB-1 exerts hair growth-promoting effects by augmenting Wnt/β-catenin signaling in human dermal papilla cells (v0.1)"
The natural compound VB-1, found in a Chinese herb, can promote hair growth by boosting cell activity in human skin cells.
research Liposomes and Follicular Penetration
Liposomes can improve hair care and treat hair issues effectively.
research 1032 Characterization of the human scalp hair follicle microbiome reveals differential spatial distribution, abundance and viability of intrafollicular microbiota and modulation of hair growth and metabolism by staphylococcus epidermidis
Staphylococcus epidermidis affects hair growth and metabolism, suggesting it could help manage hair growth issues.
research Dissolving microneedles: Applications and growing therapeutic potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Riboflavin-Sensitized Photo-Acceleration of Food-Grade Pigment Formation: Kinetic Insights, Mechanistic Analysis, and Application in Rapid Hair Coloration
Riboflavin with blue light speeds up hair dyeing, making it faster, safer, and long-lasting with less hair damage.
research The hair cycle and Vitamin D receptor
Vitamin D receptor is essential for healthy hair growth.
research L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes
The hair-growth formula with L-cystine helps protect and grow hair cells.
research Cholesterol homeostasis in hair follicle keratinocytes is disrupted by impaired ABCA5 activity
Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.
research Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation
Caffeine in shampoo quickly enters the body through hair follicles.
research Passive and Iontophoretic Delivery of Three Diclofenac Salts across Various Skin Types.
Diclofenac salt delivery through skin varies based on the salt's counterions.
research THBS4 promotes hair regeneration by inducing dermal mechanical niche adaptation
The study highlights the crucial role of THBS4 in hair regeneration by modulating the mechanical properties of the dermal niche, which reduces matrix stiffness and enhances interactions between the epidermis and dermis. This process activates hair follicle stem cells (HFSCs) and accelerates the transition from the telogen to anagen phase, promoting hair growth. THBS4 upregulation in dermal fibroblasts activates signaling pathways involving ITGB1, EGR1, and HMGCR, facilitating HFSC proliferation. Experiments with mice and organoids showed that THBS4 treatment significantly enhances hair regeneration, suggesting its potential as a therapeutic target for hair loss treatments. Further research is needed to explore the detailed mechanisms of THBS4 in extracellular matrix assembly and metabolic reprogramming.
research Unlocking Hair Follicles as Drug Reservoirs: Advances in Transfollicular Drug Delivery
Hair follicles can be used to deliver drugs effectively, especially with nanoparticles, for treating skin conditions.
research TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro
TRPV4 slows hair growth by affecting hair follicle cells.
research Impact of Consciousness Energy Healing Treatment on the Telogen Skin of Hair Follicles of C57BL/6 Mice
Biofield Energy Healing may help hair growth and skin health.
research Cyclic ADP-Ribose Modulates Intracellular Calcium Homeostasis and Anagen-Associated Signaling Pathways in Human Hair Follicle Dermal Papilla Cells
Cyclic ADP-ribose helps regulate calcium and signals that promote hair growth in hair follicle cells.
research Study on the Activity of Sheep High-sulfur Keratin Promoter
The B2C promoter works in sheep cells but not in mouse embryos.
research Non-invasive analysis of penetration and storage of Isoconazole nitrate in the stratum corneum and the hair follicles
Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.
research Hair growth promoting activity of discarded biocomposite keratin extract
Keratin extract from human hair was found to promote hair growth in mice.
research [Evaluation of vitamin B6 and calcium pantothenate effectiveness on hair growth from clinical and trichographic aspects for treatment of diffuse alopecia in women].
Vitamin B6 reduced hair loss in women with diffuse alopecia, but calcium pantothenate had no clear positive effect.